Title:
TRANSDUCING COMBINATORIAL PEPTIDE LIBRARY
Document Type and Number:
WIPO Patent Application WO2005035552
Kind Code:
A3
Abstract:
This invention provides methods for isolating bio-active molecules from complex, rationally designed peptide libraries with a reduction in assay time and increase in throughput. The molecules have the ability to facilitate transport across biological membranes. The methods also identify bio-active peptides of therapeutic value such as vaccines in treating cancers, viral diseases, and autoimmune diseases, as well as to identify useful clinical diagnostic reagents.
Inventors:
NICOLETTE CHARLES A (US)
Application Number:
PCT/US2004/033278
Publication Date:
September 01, 2005
Filing Date:
October 06, 2004
Export Citation:
Assignee:
GENZYME CORP (US)
NICOLETTE CHARLES A (US)
NICOLETTE CHARLES A (US)
International Classes:
C07K1/04; G01N33/53; C07K; (IPC1-7): G01N33/53
Foreign References:
| US5846841A | 1998-12-08 | |||
| US5858670A | 1999-01-12 | |||
| US6338945B1 | 2002-01-15 |
Other References:
OHLMEYER M. ET AL.: "Complex synthetic chemical libraries indexed with molecular tags.", PNAS USA, vol. 90, December 1993 (1993-12-01), pages 10922 - 10926, XP000829535
DOOLEY C.T. ET AL.: "An all d-amino acid opioid peptide with central analgesic", SCIENCE., vol. 266, December 1994 (1994-12-01), pages 2019 - 2022, XP002955242
DOOLEY C.T. ET AL.: "An all d-amino acid opioid peptide with central analgesic", SCIENCE., vol. 266, December 1994 (1994-12-01), pages 2019 - 2022, XP002955242
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