Title:
TREATMENT OF METASTATIC DISEASE
Document Type and Number:
WIPO Patent Application WO2001012172
Kind Code:
B1
Abstract:
The present invention is directed to compounds and methods for the treatment of metastatic disease. The compounds of this invention have specificity for EphA2, an epithelial cell tyrosine kinase that is overexpressed in metastatic tumor cells. The compounds used in accordance with this invention may be provided in a pharmaceutical composition for treatment of metastatic disease.
Inventors:
KINCH MICHAEL SCOTT
Application Number:
PCT/US2000/022670
Publication Date:
August 16, 2001
Filing Date:
August 17, 2000
Export Citation:
Assignee:
PURDUE RESEARCH FOUNDATION (US)
International Classes:
A61K38/00; A61K38/19; A61K39/395; A61K45/00; A61P35/04; C07K16/30; G01N33/573; C07K16/32; C12N5/07; C12N5/09; C12N15/02; C12P21/08; G01N33/574; (IPC1-7): A61K31/00; A61K39/395; A61K49/00; C07K2/00; C07K5/00; C07K16/28
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