Title:
USE OF AMINOGLYCOSIDE RESISTANCE GENE
Document Type and Number:
WIPO Patent Application WO2003027300
Kind Code:
A3
Abstract:
Use of aminoglycoside resistance gene product for achieving high-density growth of animal cells.
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Inventors:
AL-RUBEAI MOHAMED (GB)
PERANI ANGELO (GB)
RACHER ANDY (GB)
BIRCH JOHN (GB)
PERANI ANGELO (GB)
RACHER ANDY (GB)
BIRCH JOHN (GB)
Application Number:
PCT/GB2002/004522
Publication Date:
August 21, 2003
Filing Date:
September 26, 2002
Export Citation:
Assignee:
LONZA BIOLOGICS PLC (GB)
AL-RUBEAI MOHAMED (GB)
PERANI ANGELO (GB)
RACHER ANDY (GB)
BIRCH JOHN (GB)
AL-RUBEAI MOHAMED (GB)
PERANI ANGELO (GB)
RACHER ANDY (GB)
BIRCH JOHN (GB)
International Classes:
C12N5/10; C12N15/65; C12N15/85; C12N15/09; C12P21/02; (IPC1-7): C12N15/85; C12N9/12; C12P21/02
Domestic Patent References:
| WO1989001028A1 | 1989-02-09 | |||
| WO2001051615A1 | 2001-07-19 |
Other References:
HAYDEN M S ET AL: "Antibody engineering", CURRENT OPINION IN IMMUNOLOGY, CURRENT BIOLOGY LTD, XX, vol. 9, no. 2, April 1997 (1997-04-01), pages 201 - 212, XP004327252, ISSN: 0952-7915
SCHWARTZ J L ET AL: "Production of recombinant herpes simplex virus protease in 10-L stirred vessels using a baculovirus-insect cell expression system.", JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, vol. 19, no. 2, 1997, pages 87 - 91, XP002243886
SINACORE M S ET AL: "ADAPTATION OF MAMMALIAN CELLS TO GROWTH IN SERUM-FREE MEDIA", MOLECULAR BIOTECHNOLOGY, TOTOWA, NJ, US, vol. 15, no. 3, July 2000 (2000-07-01), pages 249 - 257, XP009001160, ISSN: 1073-6085
ELIAS CYNTHIA B ET AL: "Enhanced growth of Sf-9 cells to a maximum density of 5.2 X 107 cells per mL and production of beta-galactosidase at high cell density by fed batch culture.", BIOTECHNOLOGY AND BIOENGINEERING, vol. 68, no. 4, 20 May 2000 (2000-05-20), pages 381 - 388, XP002243887, ISSN: 0006-3592
YOO E M ET AL: "Myeloma expression systems", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 261, no. 1-2, 1 March 2002 (2002-03-01), pages 1 - 20, XP004341264, ISSN: 0022-1759
SCHWARTZ J L ET AL: "Production of recombinant herpes simplex virus protease in 10-L stirred vessels using a baculovirus-insect cell expression system.", JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, vol. 19, no. 2, 1997, pages 87 - 91, XP002243886
SINACORE M S ET AL: "ADAPTATION OF MAMMALIAN CELLS TO GROWTH IN SERUM-FREE MEDIA", MOLECULAR BIOTECHNOLOGY, TOTOWA, NJ, US, vol. 15, no. 3, July 2000 (2000-07-01), pages 249 - 257, XP009001160, ISSN: 1073-6085
ELIAS CYNTHIA B ET AL: "Enhanced growth of Sf-9 cells to a maximum density of 5.2 X 107 cells per mL and production of beta-galactosidase at high cell density by fed batch culture.", BIOTECHNOLOGY AND BIOENGINEERING, vol. 68, no. 4, 20 May 2000 (2000-05-20), pages 381 - 388, XP002243887, ISSN: 0006-3592
YOO E M ET AL: "Myeloma expression systems", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 261, no. 1-2, 1 March 2002 (2002-03-01), pages 1 - 20, XP004341264, ISSN: 0022-1759
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