Title:
USE OF A PA131 POLYPEPTIDE IN TREATMENT OF ATHEROSCLEROSIS
Document Type and Number:
WIPO Patent Application WO2006102072
Kind Code:
A3
Abstract:
Use of a PAl 31 polypeptide for treatment of atherosclerosis is described. PA131 polypeptides useful in the described regimens and compositions include human and murine PA131 polypeptides.
Inventors:
LEBHERZ CORINNA (DE)
WHITE JOHN R (US)
WILSON JAMES M (US)
WHITE JOHN R (US)
WILSON JAMES M (US)
Application Number:
PCT/US2006/009699
Publication Date:
November 23, 2006
Filing Date:
March 17, 2006
Export Citation:
Assignee:
UNIV PENNSYLVANIA (US)
SMITHKLINE BEECHAM CORP DBA GL (US)
LEBHERZ CORINNA (DE)
WHITE JOHN R (US)
WILSON JAMES M (US)
SMITHKLINE BEECHAM CORP DBA GL (US)
LEBHERZ CORINNA (DE)
WHITE JOHN R (US)
WILSON JAMES M (US)
International Classes:
A61K38/16; A61P9/10
Domestic Patent References:
| WO2002038602A2 | 2002-05-16 |
Foreign References:
| EP1500663A1 | 2005-01-26 |
Other References:
LEBHERZ CORINNA ET AL: "Gene therapy with novel adeno-associated virus vectors substantially diminishes atherosclerosis in a murine model of familial hypercholesterolemia.", June 2004, THE JOURNAL OF GENE MEDICINE. JUN 2004, VOL. 6, NR. 6, PAGE(S) 663 - 672, ISSN: 1099-498X, XP002396575
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