Title:
THE USE OF POTASSIUM 2-(α- HYDROXYPENTYL) BENZOATE IN THE MANUFACTURE OF MEDICAMENTS FOR PREVENTING AND/OR TREATING SENILE DEMENTIA
Document Type and Number:
WIPO Patent Application WO/2010/003287
Kind Code:
A1
Abstract:
The present invention discloses the use of potassium 2-(α- hydroxypentyl) benzoate in the manufacture of medicaments for preventing, relieving or treating senile dementia diseases or symptom, and for relieving oxidative stress injury in brain tissue, increasing neural function of choline, protecting neuron and/or raising the content of brain nerve growth factor. The present invention also discloses a pharmaceutical composition comprising potassium 2-(α- hydroxypentyl) benzoate in prophylactically or therapeutically effective dose, optionally, a pharmaceutically acceptable carrier and/or adjuvant.
Inventors:
WANG XIAOLIANG (CN)
ZHAO WANHONG (CN)
YANG JINGHUA (CN)
WANG LING (CN)
LI JIANG (CN)
XU SHAOFENG (CN)
FENG NAN (CN)
MA SHIPING (CN)
ZHAO WANHONG (CN)
YANG JINGHUA (CN)
WANG LING (CN)
LI JIANG (CN)
XU SHAOFENG (CN)
FENG NAN (CN)
MA SHIPING (CN)
Application Number:
PCT/CN2008/071588
Publication Date:
January 14, 2010
Filing Date:
July 08, 2008
Export Citation:
Assignee:
INST OF MATARIA MEDICA CHINESE (CN)
WANG XIAOLIANG (CN)
ZHAO WANHONG (CN)
YANG JINGHUA (CN)
WANG LING (CN)
LI JIANG (CN)
XU SHAOFENG (CN)
FENG NAN (CN)
MA SHIPING (CN)
WANG XIAOLIANG (CN)
ZHAO WANHONG (CN)
YANG JINGHUA (CN)
WANG LING (CN)
LI JIANG (CN)
XU SHAOFENG (CN)
FENG NAN (CN)
MA SHIPING (CN)
International Classes:
A61K31/192; A61K9/08; A61K9/107; A61K9/14; A61K9/20; A61K9/48; A61P25/28; A61P43/00
Foreign References:
| CN101054346A | 2007-10-17 | |||
| CN1382682A | 2002-12-04 | |||
| CN1594270A | 2005-03-16 | |||
| CN1560018A | 2005-01-05 | |||
| CN1382682A | 2002-12-04 |
Other References:
MARSHALL: "Solid Oral Dosage Forms, Modern Pharmaceutics", vol. 7, 1979, pages: 359 - 427
See also references of EP 2332530A4
See also references of EP 2332530A4
Attorney, Agent or Firm:
BEIJING SAN GAO YONG XIN INTELLECTUAL PROPERTY AGENCY CO., LTD. (He Jing Yuan Ji Men Li, Xueyuan Road, Haidian District, Beijing 8, CN)
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