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WO/2008/087365A2 |
The invention relates to substituted 1,3-diphenylpropane derivative compounds, to pharmaceutical compositions containing same, and to the therapeutic applications thereof, especially in the fields of human and animal health.
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WO/2008/084750A1 |
Disclosed is a method for producing a compound (II) or a salt thereof, wherein a compound (I) or a salt thereof is cyclized in the presence of an optionally substituted cyclic secondary amine. (In the formulae, Ar represents an optionall...
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WO/2008/081178A1 |
In OLEDs, improved efficiency is obtained by novel compounds which can form inter alia electron injection layers of the formula (I) wherein R1 is a 1 -5 ring aryl (including polycyclic), aralkyl or heteroaryl group which may be substitut...
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WO/2008/061900A1 |
The present invention discloses single site catalyst systems having anionic scorpion-like three dimensional structure, that are suitable for oligomerising or polymerising ethylene and alpha-olefins.
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WO/2008/061616A1 |
The invention relates to a process for preparing amino glycol by reacting ketoximes with ethylene oxide under basic conditions to form a substituted 2-hydroxyethyl ketoxime and subsequently reacting this with an acid to give amino glycol.
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WO/2008/054550A1 |
Infrared (IR) radiation absorbing compounds of metal or metalloids with ligands are beneficial for many applications. Schiff base biquinone (SBB) ligands surrounding a metal or metalloid center may be used for laser welding applications,...
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WO/2008/052788A1 |
The compounds and the synthesis of [F-18]-labeled L-glutamic acid, [F-18]-labeled L-glutamate, derivatives thereof of the formula (I) and uses thereof are described.
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WO/2008/050313A1 |
This invention relates to novel iminium salts, which may be in the form of ionic liquids, and a process for producing electron deficient olefins, such as 2-cyanoacrylates, using such an iminium salt, for instance in the form of an ionic ...
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WO/2008/050661A1 |
Disclosed is a method for producing an asymmetric copper complex crystal wherein a crystallization process is performed in the presence of an alcohol solvent after reacting an optically active salicylideneaminoalcohol compound with a cop...
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WO/2008/051244A2 |
The present invention is directed to compounds of formula (I): wherein R1 is selected from the group consisting of -C(O)R and (a), wherein R6 and R7 are independently selected from H, alkyl, cycloalkyl, heterocycloalkyl, heteroaryl or ar...
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WO/2008/038578A1 |
Disclosed are an optically active quaternary ammonium salt having axial asymmetry and a method for producing an α-amino acid and a derivative thereof by using the quaternary ammonium salt. The optically active quaternary ammonium salt h...
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WO/2008/035359A2 |
The present invention discloses oximinophenoxyalkanoic acid and phenylalkanoic acid of the general formula (I) their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing t...
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WO/2008/032453A1 |
Disclosed is a commercially advantageous method for producing a hydrazone represented by the formula (4) below. Specifically disclosed is a method for producing a hydrazone according to the following reaction formula.
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WO/2008/030039A1 |
Disclosed are a diimmonium salt and a near infrared ray absorption film including the same which is used for blocking the near infrared ray. The diimmonium salt for a near infrared ray absorption film is represented by Formula 1 of the s...
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WO/2008/015133A2 |
The present invention relates to a novel process for preparing amidrazones of the formula (I) wherein R, R1, R2, A, B, W, Y and n have the meanings as indicated in the description. Further, the invention relates to novel compounds used a...
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WO/2008/015160A1 |
The present invention discloses metallic complexes based on oxime-ether ligand and their use in oligomerisation and in polymerisation of ethylene and alpha-olefins.
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WO/2008/010474A1 |
A charge-transporting varnish comprising a phenylamino-N,N'-diphenylquinonediimine derivative represented by the formula (1) as a charge-transporting substance. It becomes possible to provide a charge-transporting varnish comprising an o...
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WO/2007/147880A1 |
The present invention relates to substituted 1,3-diphenylpropane derivatives, to the pharmaceutical compositions containing them and to the therapeutic uses thereof, in particular in the fields of human and animal health.
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WO/2007/147879A1 |
The present invention relates to substituted 1,3-diphenylpropane derivatives, to the pharmaceutical compositions containing them and to the therapeutic uses thereof, in particular in the fields of human and animal health.
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WO/2007/148435A1 |
A process for producing an ester or an alcohol using a fluoroimidinium sulfonate derivative represented by the general formula (9) or a fluoroimidinium carboxylate derivative represented by the general formula (6) and using an alcohol wi...
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WO/2007/127639A2 |
This invention relates to novel homotopic prodrugs and medicaments and methods for their preparation, testing and use. In one embodiment, the homotopic prodrug has the general formula (I) wherein (II) is a biologically-active moiety comp...
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WO/2007/124920A1 |
The present invention relates to a process for making substantially pure racemic sertraline or its pharmaceutically acceptable salts having a cis/trans ratio of greater than about 85: 15% and which is substantially free of its deschloro ...
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WO/2007/118896A1 |
The present invention relates to new O-carboxymethyl oxime ether compounds which are useful for combating arthropod pests, in particular insects or arachnids. This object is achieved by compounds of formula (I) as defined below and by th...
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WO/2007/119434A1 |
A pyridazinone compound represented by the formula (I) have excellent effect on weed control and are useful as an active ingredient of herbicides.
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WO/2007/118681A1 |
The invention relates to a method for producing 8-aryl-octanoyl derivatives, especially chiral 8-aryl-octanoyl amides, as well as novel intermediate products that are used in said method for producing the inventive octanoyl derivatives, ...
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WO/2007/120502A1 |
A compound of formula (I): wherein R is -CH2OH, -C(O)H, -C(OR3)2H, -C(OR4)(OH)H, -CH=NC6H4C(O)OR5 or -CH=NR6; R1 and R2 are each independently H or CH3; R3 and R4 are each independently H or a straight or branched aliphatic group having ...
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WO/2007/117462A1 |
A compound of formula (I): wherein R is -CH2OH, -C(O)H5 -C(OR3)2H, -C(OR4)(OH)H, -CH=NC6H4C(O)OR5 or -CH=NR6; R1 and R2 are each independently H or CH3; R3 and R4 are each independently H or a straight or branched aliphatic group having ...
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WO/2007/116112A1 |
The present invention relates to a method for preparing oxymes that comprises catalytic hydrogenation of the corresponding a, ß-unsaturated nitrocompound using a gold catalyst.
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WO/2007/110548A1 |
The invention relates to a process of diastereoselective synthesis. This process carries out the diastereoselective alkylation of optically active nopinone to form the compound of formula (I) according to scheme A below, in which: R repr...
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WO/2007/105814A1 |
Disclosed is a novel pest control agent, particularly an insecticide or an acaricide. Specifically disclosed is a substituted isoxazoline compound represented by the general formula (1) below or a salt thereof. Also disclosed is a pest c...
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WO/2007/099385A1 |
The present invention relates to dipeptidyl peptidase IV (DPP-IV) inhibitors of formula (1), pharmaceutical compositions containing them, processes for their preparation, and methods for treating disorders mediated by DPP-IV inhibition, ...
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WO/2007/098474A1 |
Compounds I and II that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors.
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WO/2007/097368A1 |
Disclosed is a diimmonium salt having a structure represented by the following formula (1). (1) In the formula (1), X represents anions necessary for neutralizing the electric charge, and at least one of R1-R8 represents a group selected...
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WO/2007/091396A1 |
Disclosed is a compound having S1P receptor antagonist activity, which is useful as an immunosuppressive agent. The compound has few side effects, and is orally administrable. Specifically disclosed are a compound represented by the gene...
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WO/2007/090434A1 |
The invention relates to compounds of the formula (I) in which A1, A2, R1, R2, R3, R4, R5 and X have the definition specified in the description, to processes and intermediates for preparing them and to their use for controlling pests.
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WO/2007/091406A1 |
A compound represented by the following general formula (I). (I) (In the formula, R1 represents hydrogen, C1-8 alkyl, C6-20 aryl, or C7-20 arylalkyl; R2 represents hydrogen, C1-18 alkyl, halogeno, nitro, cyano, or amino; n is a number of...
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WO/2007/089022A1 |
Disclosed is a method for producing an optically active alcohol compound, which is characterized in that a cyclic ether compound and a phenol compound are reacted in the presence of an asymmetric complex which is obtained by reacting an ...
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WO/2007/088878A1 |
Disclosed is a commercial method which is practically suitable for producing a 2-iminocarboxylic acid derivative and a benzazepinone by a short process under mild conditions. Specifically disclosed is a method for producing a benzazepino...
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WO/2007/089025A1 |
Disclosed is a method for producing an optically active alcohol compound, which is characterized in that a cyclic ether compound and a phenol compound are reacted in the presence of an asymmetric complex which is obtained by reacting an ...
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WO/2007/086584A1 |
Disclosed is a compound which can inhibit both of FabI and FabK which are fatty acid synthases to show a wide antibacterial spectrum including Streptococcus pneumoniae, Pseudomonas aeruginosa and Enterococcus faecalis, and therefore can ...
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WO/2007/084162A2 |
Provided herein are compositions and methods for treating or preventing cancer and autoimmune diseases. Compositions comprise a sirtuin inhibitory compound that decreases the activity of a sirtuin, such as SIRTl or Sir2. Exemplary method...
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WO/2007/079930A1 |
The present invention relates to substituted cyclohexylmethyl derivatives, to processes for preparing them, to pharmaceuticals comprising these compounds, and to the use of substituted cyclohexylmethyl derivatives for producing pharmaceu...
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WO/2007/080947A1 |
Disclosed is a compound represented by the following general formula (1). (1) In the formula, A and B independently represent a substituted or unsubstituted heterocyclic group or a substituted or unsubstituted condensed polycyclic hydroc...
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WO/2007/077469A1 |
The present invention relates to dihydro-2,3-benzodiazepine compounds of high enantiomeric purity according to the general formula (I), which contain an asymmetric centre at the position 4 of the dihydro-2,3-benzodiazepine compound, and ...
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WO/2007/073000A1 |
A method for producing a compound of formula (I), which comprises reducing a compound of formula (II) with a hydrazine compound: wherein R103, R113, R123, R133, R143, R203, R213, R223, R233 and R243 represent a substituent; the other Rs ...
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WO/2007/071497A1 |
Compounds of the Formula (I) and (II) wherein M1, M2 and M3 independently of one another are no bond, a direct bond, CO, O, S, SO, SO2 or NR14; provided that at least one of M1, M2 or M3 is a direct bond, CO, O, S, SO, SO2 or NR14; M4 is...
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WO/2007/069773A1 |
The present invention provides a novel modulator of the TRPV1-receptor function, comprising a compound of the formula; wherein ring A is an optionally substituted carbocycle or heterocycle, ring B is an optionally substituted benzene rin...
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WO/2007/065567A1 |
Process for preparing compounds of the formula (IX) by a) reacting haloalkyl(thio)acetic acids of the formula (II) with formamides of the formula (III) to vinimidinium salts of the formula (I), b) reacting vinimidinium salts of the formu...
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WO/2007/062183A1 |
Infrared (IR) radiation absorbing compounds of metal or metalloids with ligands are beneficial for many applications. Schiff base biquinone (SBB) ligands surrounding a metal or metalloid center may be used for laser welding applications,...
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WO/2007/058504A1 |
The present invention relates to novel compounds accelerating the activity of Peroxisome proliferator-activated receptor gamma (PPARγ) and alpha (PPARα), processes of preparing the same, and pharmaceutical compositions containing the s...
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