Title:
【発明の名称】アルファ-2アドレナリン受容体アゴニストとして有効な2-イミダゾリニルアミノインダゾール化合物
Document Type and Number:
Japanese Patent JP2001506599
Kind Code:
A
Abstract:
This invention involves compounds having structure (I) wherein: a) R1 is hydrogen; or alkyl; b) R2 is hydrogen; alkyl or nil; c) R3 is selected from hydrogen; unsubstituted C1-C3 alkanyl; amino, hydroxy, mercapto; C1-C3 alkylthio or alkoxy; C1-C3 alkylamino or C1-C3 dialkylamino; cyano; and halo; d) R4, R5 and R7 are each independently selected from hydrogen; unsubstituted C1-C3 alkanyl, alkenyl or alkynyl; cycloalkanyl, cycloalkenyl; unsubstitued C1-C3 alkylthio or alkoxy; hydroxy; thio; nitro; cyano; amino; C1-C3 alkylamino or C1-C3 dialkylamino and halo; e) when R2 is nil, bond (a) is a double bond; f) the compound is not 7-bromo-6-(2-imidazolinylamino)indazole; and enantiomers, optical isomers, stereoisomers, diastereomers, tautomers, addition salts, biohydrolyzable amides and esters, and pharmaceutical compositions containing such novel compounds, and the use of such compounds for preventing or treating disorders modulated by alpha-2 adrenoceptors.
More Like This:
| JP4912148 | New imidazolidine derivative |
| JP2006188529 | IMIDE AS TNFα INHIBITOR |
| JP2023060020 | COMPOUNDS, COMPOSITIONS AND METHODS |
Inventors:
Capsu, Thomas, Lee.
Bogdan, Sophie, Eve.
Henry, Raymond, Todd.
Sheldon, Russell, James.
Sebel, William, Lee.
Ares, Jeffrey, Joseph.
Bogdan, Sophie, Eve.
Henry, Raymond, Todd.
Sheldon, Russell, James.
Sebel, William, Lee.
Ares, Jeffrey, Joseph.
Application Number:
JP52468698A
Publication Date:
May 22, 2001
Filing Date:
November 21, 1997
Export Citation:
Assignee:
THE PROCTER & GAMBLE COMPANY
International Classes:
A61K31/4178; A61P1/00; A61P9/00; A61P11/00; A61P25/00; A61P27/02; A61P27/16; A61P43/00; C07D403/12; (IPC1-7): C07D403/12; A61K31/4178; A61P1/00; A61P27/02; A61P43/00
Attorney, Agent or Firm:
Yoshikazu Tani (2 outside)