Title:
IMIDE AS TNFα INHIBITOR
Document Type and Number:
Japanese Patent JP2006188529
Kind Code:
A
Abstract:
To provide a method for lowering the TNFα level of mammals, a compound and a composition useful for the method and an imide acting as a TNFα inhibitor.
Imides act as inhibitors of tumor necrosis factor α and can be used to combat cachexia, endotoxic shock, and retrovirus replication.
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Inventors:
MULLER GEORGE W (US)
Application Number:
JP2006039633A
Publication Date:
July 20, 2006
Filing Date:
February 16, 2006
Export Citation:
Assignee:
CELGENE CORP (US)
MULLER GEORGE W (US)
MULLER GEORGE W (US)
International Classes:
C07D209/48; C07D307/66; A61K31/16; A61K31/165; A61K31/215; A61K31/275; A61K31/33; A61K31/34; A61K31/341; A61K31/40; A61K31/4015; A61K31/403; A61K31/4035; A61K31/404; A61K31/405; A61K31/415; A61K31/4178; A61K31/4188; A61K31/435; A61K31/437; A61K31/44; A61K31/4406; A61K31/4427; A61K31/443; A61K31/4439; A61K31/4465; A61K31/45; A61K31/454; A61K31/4545; A61P1/04; A61P9/04; A61P9/10; A61P11/00; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P21/00; A61P25/00; A61P29/00; A61P31/04; A61P31/12; A61P31/14; A61P31/16; A61P31/18; A61P31/20; A61P31/22; A61P33/06; A61P35/00; A61P37/00; A61P37/04; A61P37/06; A61P43/00; C07C229/08; C07C229/20; C07C229/22; C07C229/34; C07C237/04; C07C255/50; C07C275/42; C07D209/08; C07D209/18; C07D209/46; C07D209/66; C07D209/76; C07D211/88; C07D213/55; C07D213/75; C07D401/04; C07D401/06; C07D401/12; C07D403/06; C07D405/12; C07D471/04; C07D487/04; C07D495/04
Attorney, Agent or Firm:
Mikio Hatta
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