Title:
PROCESS FOR PRODUCTION OF HYDROXYLATED ADAMANTANE USING MICROORGANISM
Document Type and Number:
WIPO Patent Application WO/2007/114125
Kind Code:
A1
Abstract:
Disclosed is a process for production of an N-(monohydroxy-2-adamantyl)-phthalimide derivative, which is a compound useful as an intermediate for the production of a functional resin or pharmaceutical, in a high yield and at a low cost. A mold isolated from soil and belonging to the genus Nakataea, Rhizoctonia or Chaetomium can produce an N-(monohydroxy-2-adamantyl)-phthalimide derivative from an N-(2-adamantyl)-phthalimide derivative in a culture medium in a high yield.
Inventors:
MITSUDA YUUICHI (JP)
MINAGAWA KAZUYUKI (JP)
OGAWA TOMOYUKI (JP)
MINAGAWA KAZUYUKI (JP)
OGAWA TOMOYUKI (JP)
Application Number:
PCT/JP2007/056542
Publication Date:
October 11, 2007
Filing Date:
March 28, 2007
Export Citation:
Assignee:
SHIONOGI & CO (JP)
MITSUDA YUUICHI (JP)
MINAGAWA KAZUYUKI (JP)
OGAWA TOMOYUKI (JP)
MITSUDA YUUICHI (JP)
MINAGAWA KAZUYUKI (JP)
OGAWA TOMOYUKI (JP)
International Classes:
C12P17/10; C07D209/48; C12N1/14; C12R1/645
Domestic Patent References:
| WO2004056744A1 | 2004-07-08 |
Other References:
NYVALL R.F. ET AL.: "Development of Fungal Brown Spot and Spot Blotch on Cultivated Wild Rice in Minnesota", PLANT DISEASE, vol. 83, no. 10, 1999, pages 936 - 938, XP003018055
LIU Z.L. ET AL.: "Polymorphism of Genes Coding for Nuclear 18S rRNA Indicates Genetic Distinctiveness of Anastomosis Group 10 from Other Groups in the Rhizoctonia solani Species Complex", APPL. ENVIRON. MICROBIOL., vol. 61, no. 7, 1995, pages 2659 - 2664, XP002124048
WAKSMAN S.A. ET AL.: "Chaetomin, a New Antibiotic Substance Produced by Chaetomium cochliodes: I. Formation and Properties", J. BACTERIOL., vol. 48, no. 5, 1944, pages 527 - 530, XP003018056
JOHNSON R.A. ET AL.: "Selective Oxygenation of Adamantanes and Other Substrates by Beauveria sulfurescens", J. ORG. CHEM., vol. 57, no. 26, 1992, pages 7209 - 7212, XP003018057
HERR M.E. ET AL.: "The Microbiological Oxygenation of Acylated 1-Adamantanamines. Stereochemistry and Structural Determinations", J. ORG. CHEM., vol. 33, no. 8, 1968, pages 3201 - 3207, XP003018058
LIU Z.L. ET AL.: "Polymorphism of Genes Coding for Nuclear 18S rRNA Indicates Genetic Distinctiveness of Anastomosis Group 10 from Other Groups in the Rhizoctonia solani Species Complex", APPL. ENVIRON. MICROBIOL., vol. 61, no. 7, 1995, pages 2659 - 2664, XP002124048
WAKSMAN S.A. ET AL.: "Chaetomin, a New Antibiotic Substance Produced by Chaetomium cochliodes: I. Formation and Properties", J. BACTERIOL., vol. 48, no. 5, 1944, pages 527 - 530, XP003018056
JOHNSON R.A. ET AL.: "Selective Oxygenation of Adamantanes and Other Substrates by Beauveria sulfurescens", J. ORG. CHEM., vol. 57, no. 26, 1992, pages 7209 - 7212, XP003018057
HERR M.E. ET AL.: "The Microbiological Oxygenation of Acylated 1-Adamantanamines. Stereochemistry and Structural Determinations", J. ORG. CHEM., vol. 33, no. 8, 1968, pages 3201 - 3207, XP003018058
Attorney, Agent or Firm:
TAKAYAMA, Hirotsugu et al. (Intellectual Property Department,12-4, Sagisu 5-chome,Fukushima-ku, Osaka-shi, Osaka 02, JP)
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