Title:
CCR5アンタゴニストとして有用なピペリジン誘導体
Document Type and Number:
Japanese Patent JP2005502682
Kind Code:
A
Abstract:
The present invention provides a compound of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, R3, R9, R10, A and B are as defined in the specification. The present invention also provides pharmaceutical compositions containing the compound of this invention, and methods of treatment using the compound of this invention. The invention also relates to the use of a combination of a compound of this invention and one or more antiviral or other agents useful in the treatment of Human Immunodeficiency Virus (HIV). The invention further relates to the use of a compound of this invention, alone or in combination with another agent, in the treatment of solid organ transplant rejection, graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis.
Inventors:
Parani, Anandang
Miller, Michael W.
Scott, Jack Dee.
Miller, Michael W.
Scott, Jack Dee.
Application Number:
JP2003524986A
Publication Date:
January 27, 2005
Filing Date:
August 28, 2002
Export Citation:
Assignee:
Schering Corporation
International Classes:
C07D401/04; A61K31/4545; A61K31/506; A61K45/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P31/18; A61P37/06; A61P43/00; C07D401/14; (IPC1-7): C07D401/14; A61K31/4545; A61K31/506; A61K45/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P31/18; A61P37/06; A61P43/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita