Title:
システインプロテアーゼの阻害因子としてのピロロピリミジン
Document Type and Number:
Japanese Patent JP2005502683
Kind Code:
A
Abstract:
The invention provides compounds of Formula I or a pharmaceutically acceptable salt or ester thereof wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g. various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.
Inventors:
Claudia Beccart
Kenji Hayakawa
Osamu Irie
Junichi Sakaki
Iwasakisaki Genji
Rene Ratman
Martin Misbach
Direct delivery
Kenji Hayakawa
Osamu Irie
Junichi Sakaki
Iwasakisaki Genji
Rene Ratman
Martin Misbach
Direct delivery
Application Number:
JP2003524991A
Publication Date:
January 27, 2005
Filing Date:
August 29, 2002
Export Citation:
Assignee:
NOVARTIS AG
International Classes:
A61K31/519; A61K31/5377; A61K31/551; A61P9/00; A61P9/10; A61P11/00; A61P19/02; A61P19/10; A61P29/00; A61P31/00; A61P35/00; A61P35/04; A61P37/02; A61P37/06; A61P43/00; C07D473/00; C07D487/04; C07D519/00; (IPC1-7): C07D487/04; A61K31/519; A61K31/5377; A61K31/551; A61P9/00; A61P9/10; A61P11/00; A61P19/02; A61P19/10; A61P29/00; A61P31/00; A61P35/00; A61P35/04; A61P37/02; A61P37/06; A61P43/00; C07D519/00
Foreign References:
| US5683999A | 1997-11-04 |
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima