硫酸化部分を含むエピトープを含む単離分子、当該エピトープに対する抗体、及びその使用

Japanese Patent JP2005503756

A

The present invention provides epitopes present on cancer cells and important in physiological phenomena such as cell rolling, metastasis, and inflammation. Therapeutic and diagnostic methods and compositions using antibodies capable of binding to the epitopes are provided. Methods and compositions according to the present invention can be used in diagnosis of and therapy for such diseases as cancer, including tumor growth and metastasis, leukemia, auto-immune disease, and inflammatory disease.

Lazarovitz, Janet
Haggai, Yochevd
Praxin, daniel
Vogel, Tikva
Nimrod, Abraham
Mar-Heim, Hagit
Susanson, Esther
Richter, Tamar
Amit, Boaz
Lena Cooperman
Perez, Tubia
Lebanon, Abigder

JP2002555211A

February 10, 2005

December 31, 2001

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Survival Pharmaceuticals, Incorporated

A61K31/353; A61K31/42; A61K31/4709; A61K31/522; A61K31/5575; A61K31/616; A61K31/675; A61K31/7072; A61K31/711; A61K31/727; A61K31/728; A61K35/12; A61K38/00; A61K39/00; A61K39/395; A61K51/00; A61P7/02; A61P9/10; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/02; C07K2/00; C12N15/09; C07K14/47; C07K16/18; C07K16/30; (IPC1-7): C12N15/09; A61K31/353; A61K31/42; A61K31/4709; A61K31/522; A61K31/5575; A61K31/616; A61K31/675; A61K31/7072; A61K31/711; A61K31/727; A61K31/728; A61K38/00; A61K39/395; A61K51/00; A61P7/02; A61P9/10; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/02; C07K14/47; C07K16/18

Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama

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