I.A.慢性関節リウマチの治療においてp38キナーゼ阻害剤として使用される縮合ヘテロアリール誘導体

Japanese Patent JP2005538100

A

Compounds of formula (I): wherein A is a 5-membered heteroaryl ring are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38, such as rheumatoid arthritis.

JP5687259	p38 inhibitor and its usage
JP2011520954	Phenyl or pyridinyl substituted indazole derivatives
WO/2011/043479	THERAPEUTIC AGENT FOR CEREBRAL INFARCTION

Angel, richard, martin
Baldwin, Ian, Robert
Bumborough, Paul
Deboeck, niger, mark
Long Staff, Timothy
Swanson, Stephen

JP2004523985A

December 15, 2005

July 30, 2003

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SmithKline Beechham Corporation

A61K31/416; A61K31/427; A61K31/454; A61K31/4545; A61K31/496; A61K31/5377; A61P1/00; A61P1/02; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P11/00; A61P11/06; A61P17/06; A61P19/00; A61P19/06; A61P21/00; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P33/06; A61P35/00; A61P37/08; A61P43/00; C07D231/56; C07D261/20; C07D277/82; C07D403/12; C07D405/12; C07D409/04; C07D409/12; C07D413/04; C07D413/12; C07D413/14; C07D417/12; C07D417/14; (IPC1-7): C07D231/56; A61K31/416; A61K31/427; A61K31/454; A61K31/4545; A61K31/496; A61K31/5377; A61P1/00; A61P1/02; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P11/00; A61P11/06; A61P17/06; A61P19/00; A61P19/06; A61P21/00; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P33/06; A61P35/00; A61P37/08; A61P43/00; C07D261/20; C07D405/12; C07D409/04; C07D413/04; C07D413/12; C07D413/14; C07D417/12; C07D417/14

WO2002055517A2	2002-07-18
WO2002055517A2	2002-07-18

Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ai Fujii

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