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Title:
プロテアーゼ阻害剤に対する病原性ウイルスの感受性を決定するための組成物および方法
Document Type and Number:
Japanese Patent JP2006506967
Kind Code:
A
Abstract:
The present invention provides an approach for developing an algorithm for determining the effectiveness of anti-viral drugs based on a comprehensive analysis of paired phenotypic and genotypic data guided by phenotypic clinical cut-offs. In one aspect, the algorithm allows one to provide a patient with effective treatment. It helps predict whether an infected individual will respond to treatment with an anti-viral compound, thereby allowing an effective treatment regimen to be designed without subjecting the patient to unnecessary side effects. Also, by avoiding the administration of ineffective drugs, considerable time and money is saved.

Inventors:
Chappie, Colombe
Petropoulos, Christos, Jay.
Perkin, Neil, Tea.
Application Number:
JP2004518241A
Publication Date:
March 02, 2006
Filing Date:
July 01, 2003
Export Citation:
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Assignee:
Birologic, Incorporated
International Classes:
C12N15/09; C07H21/00; C12Q1/37; C12Q1/68; C12Q1/70; G01N
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Yuko Matsuniya