Title:
血管新生において差次的に発現するESM-1遺伝子、そのアンタゴニスト、および、それらを使用する方法
Document Type and Number:
Japanese Patent JP2006506966
Kind Code:
A
Abstract:
The invention relates a nucleic acid and its encoded polypeptide ESM-1, whose expression is modulated in angiogenesis and oncogenesis. The invention also relates to antibodies having specificity for said polypeptide. The present invention also relates to antisense molecules. The invention further relates to methods useful for treating or modulating angiogenesis in mammals in need of such biological effect.
Inventors:
Griggs, David W
Head, richard dee
Mazarella, Richard A.
Wayne Stein, Edward Jay
Head, richard dee
Mazarella, Richard A.
Wayne Stein, Edward Jay
Application Number:
JP2004518180A
Publication Date:
March 02, 2006
Filing Date:
July 01, 2003
Export Citation:
Assignee:
Pharmacia Corporation
International Classes:
C12N15/09; A01K67/027; A61K38/00; A61K39/395; A61P9/00; A61P35/00; C07K14/47; C07K16/18; C07K19/00; C12M1/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/68; G01N37/00; C12P21/08
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Kiyoshi Murakami
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Kiyoshi Murakami
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