Title:
ケトアミノ酸の部位特異的蛋白質組込み方法
Document Type and Number:
Japanese Patent JP2006507814
Kind Code:
A
Abstract:
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases, which incorporate keto amino acids into proteins are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins with keto amino acids using these orthogonal pairs.
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Inventors:
Peter G. Schultz
Ray One
Ray One
Application Number:
JP2004545280A
Publication Date:
March 09, 2006
Filing Date:
October 15, 2003
Export Citation:
Assignee:
THE SCRIPPS RESEARCH INSTITUTE
International Classes:
C12N15/09; C07K14/47; C12N1/21; C12N9/00; C12N9/10; C12N15/10; C12N15/67; C12P21/00
Attorney, Agent or Firm:
Kazuho Kawarada