ペプチドデホルミラーゼ阻害剤としてのイソキサゾール類

Title:

ペプチドデホルミラーゼ阻害剤としてのイソキサゾール類

Document Type and Number:

Japanese Patent JP2007505050

Kind Code:

A

Abstract:

Isoxazole compounds of formula (I) and pharmaceutically acceptable salts or esters thereof are peptide deformylase inhibitors useful in the treatment or prevention of infections and other disease in which peptide deformylases are involved, especially in the treatment of bacterial and parasitic infections, for example infections fully or partly caused by microorganisms belonging to Staphylococcus, Enterococcus, Streptococcus, Haemophilus, Moraxella, Escherichia, Mycobacterium, Mycoplasma, Pseudomonas, Chlamydia, Rickettsia, Klebsiella, Shigella, Salmonella, Bordetella, Clostridium, Helicobacter, Campylobacter, Legionella or Neisseria.

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Inventors:

Cali, Patrizia
Hegel Menkrantz, Andels
Nerum, Lars

Application Number:

JP2006525630A

Publication Date:

March 08, 2007

Filing Date:

September 10, 2004

Export Citation:

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Assignee:

ARPIDA A/S

International Classes:

C07D261/18; A61K31/42; A61K31/422; A61K31/506; A61P31/00; A61P31/04; A61P43/00; C07D261/12; C07D413/12; C07D413/14

Attorney, Agent or Firm:

Shintaro Nogawa

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