Title:
コンセンサス/先祖免疫原
Document Type and Number:
Japanese Patent JP2007505624
Kind Code:
A
Abstract:
The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralize a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.
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Inventors:
Highness, Burton F.
Gao, Feng
Cove, Bette Tea.
Hearn, Beatris H.
Shaw, George M.
Koza, Dennis
Re-in-in
Decker, Julie
Riao, Hua-sin
Gao, Feng
Cove, Bette Tea.
Hearn, Beatris H.
Shaw, George M.
Koza, Dennis
Re-in-in
Decker, Julie
Riao, Hua-sin
Application Number:
JP2006527030A
Publication Date:
March 15, 2007
Filing Date:
September 17, 2004
Export Citation:
Assignee:
Duke University
The University of Alabama at Birmingham Research Foundation
The University of Alabama at Birmingham Research Foundation
International Classes:
C12N15/09; A61K31/7088; A61K38/00; A61K39/00; A61K39/21; A61K48/00; A61P31/18; A61P37/04; C07H21/04; C07K14/155; C12N5/02; C12N15/74; C12N
Domestic Patent References:
| JP2003523188A | 2003-08-05 |
Other References:
JPN6010036708, Ｓｃｉｅｎｃｅ, 2002, Ｖｏｌ．２９６, ｐ．２３５４−２３６０
JPN6010036709, Ｓｃｉｅｎｃｅ, 200303, Ｖｏｌ．２９９, ｐ．１５１５−１５１８
JPN5006013915, ＬＥＩＴＮＥＲ， Ｔ．, ＨＩＶ ＳＥＱＵＥＮＣＥ ＣＯＭＰＥＮＤＩＵＭ ２００３, Ｐ． Ｉ−ＶＩＩＩ， ５１３−５７３
JPN6010036709, Ｓｃｉｅｎｃｅ, 200303, Ｖｏｌ．２９９, ｐ．１５１５−１５１８
JPN5006013915, ＬＥＩＴＮＥＲ， Ｔ．, ＨＩＶ ＳＥＱＵＥＮＣＥ ＣＯＭＰＥＮＤＩＵＭ ２００３, Ｐ． Ｉ−ＶＩＩＩ， ５１３−５７３
Attorney, Agent or Firm:
Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Ryo Hashimoto
Tetsuya Kazama
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Ryo Hashimoto
Tetsuya Kazama