桂皮酸アミド類、それらの調製方法、ならびにそれらを含む医薬組成物

Title:

桂皮酸アミド類、それらの調製方法、ならびにそれらを含む医薬組成物

Document Type and Number:

Japanese Patent JP2007523919

Kind Code:

A

Abstract:

E-cinnamic amides of piperazine derivatives according to formula (I) wherein X is chloro or fluoro and R¹is an aromatic or heteroaromatic group, their pharmaceutically acceptable salts or solvates. The invention also relates to pharmaceutical compositions containing a compound of formula (I) together with a pharmaceutically acceptable carrier. Included are also processes for the preparation of compounds of formula (I), as well as methods for treating mammals suffering from inflammatory, autoimmune, proliferative or hyperproliferative diseases by administering a compound having the formula (I) to said mammal.

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Inventors:

Werner Eric
Sandin Helena

Application Number:

JP2007500070A

Publication Date:

August 23, 2007

Filing Date:

November 23, 2004

Export Citation:

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Assignee:

Active Biotech Abi

International Classes:

C07D241/04; A61K31/495; A61K31/496; A61K38/00; A61P1/04; A61P9/10; A61P11/06; A61P17/00; A61P25/00; A61P25/28; A61P29/00; A61P35/00; A61P37/02; A61P37/06; A61P37/08; C07D271/12; C07D285/14; C07D295/185; C07D333/60; C07D413/06; C07D417/06

Attorney, Agent or Firm:

Takakichi Hayashi

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