Title:
新規ベンゾフランおよびインドール
Document Type and Number:
Japanese Patent JP2007523920
Kind Code:
A
Abstract:
Compounds of formula (I) wherein X is a fluorine or a chlorine atom; the methyl groups located at the 2- and 5-position of the piperazine ring are in trans-configuration to each other; Y is NH or O; R1 is selected from hydrogen, chloro, bromo, nitro, methyl or trifluoromethyl; R2 is selected from hydrogen, halo, methyl, trifluoromethyl, methoxy or trifluoromethoxy; or a pharmaceutically acceptable salt or solvate thereof; The invention also relates to pharmaceutical compositions containing a compound of formula (I) together with a pharmaceutically acceptable carrier. Included are also processes for the preparation of compounds of formula (I), as well as methods for treating mammals suffering from inflammatory, autoimmune, proliferative or hyperproliferative diseases by administering a compound having the formula (I) to said mammal.
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Inventors:
Werner Eric
Sandin Helena
Sandin Helena
Application Number:
JP2007500071A
Publication Date:
August 23, 2007
Filing Date:
November 23, 2004
Export Citation:
Assignee:
Active Biotech Abi
International Classes:
C07D403/06; A61K31/496; A61P1/04; A61P9/10; A61P11/06; A61P17/00; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P37/00; A61P37/08; C07D209/42; C07D307/85; C07D405/06
Attorney, Agent or Firm:
Takakichi Hayashi