Title:
不眠症の治療において有用な新規な製剤処方
Document Type and Number:
Japanese Patent JP2008517988
Kind Code:
A
Abstract:
There is provided a formulation suitable for sublingual administration comprising zolpidem, which formulation provides inter alia a measurable plasma concentration of drug within 10 minutes of administration. The formulation is capable of providing sleep on demand, and comprises particles of drug, for example zolpidem or a pharmaceutically-acceptable salt thereof and a mucoadhesion promoting agent, such as sodium carboxymethylcellulose, which particles of drug and mucoadhesive are presented upon the surface of larger carrier particles.
Inventors:
Anders Petterson
Christer Nistrem
Suzanne Bredenberg
Christer Nistrem
Suzanne Bredenberg
Application Number:
JP2007538505A
Publication Date:
May 29, 2008
Filing Date:
October 26, 2005
Export Citation:
Assignee:
Orexo Actie Bora Get
International Classes:
A61K31/437; A61K9/00; A61K9/20; A61K31/44; A61K47/12; A61K47/26; A61K47/38; A61P25/20
Domestic Patent References:
| JPH0665103A | 1994-03-08 | |||
| JP2002363068A | 2002-12-18 |
Foreign References:
| WO2002094230A1 | 2002-11-28 | |||
| WO2001030391A2 | 2001-05-03 | |||
| WO2003059349A1 | 2003-07-24 | |||
| WO2004045589A1 | 2004-06-03 | |||
| WO2003074085A1 | 2003-09-12 | |||
| WO2003103629A1 | 2003-12-18 | |||
| WO2003103713A1 | 2003-12-18 | |||
| CN1418631A | 2003-05-21 |
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro