Title:
スクアレンを含有する水中油型エマルジョンのための品質管理法
Document Type and Number:
Japanese Patent JP2010509202
Kind Code:
A
Abstract:
Measurements of the squalene content in oil-in-water emulsions can be used as a way of checking for problems during production. In particular, it has been found that a drop in squalene content can indicate that filtration problems occurred. Testing the squalene content in the final lots is easier than investigating the characteristics of the filter, and so a squalene assay simplifies the quality control of oil-in-water emulsions.
Inventors:
Crane, Norbert
Application Number:
JP2009535148A
Publication Date:
March 25, 2010
Filing Date:
November 06, 2007
Export Citation:
Assignee:
Novartis Age
International Classes:
A61K39/39; A61K39/102; A61P31/16
Domestic Patent References:
| JP2004510747A | 2004-04-08 |
Foreign References:
| WO2006067632A2 | 2006-06-29 |
Other References:
JPN6012051909; Ｏｔｔ Ｇ ｅｔ ａｌ．: 'ＭＦ５９． Ｄｅｓｉｇｎ ａｎｄ ｅｖａｌｕａｔｉｏｎ ｏｆ ａ ｓａｆｅ ａｎｄ ｐｏｔｅｎｔ ａｄｊｕｖａｎｔ ｆｏｒ ｈｕｍａｎ ｖａｃｃｉｎｅｓ．' Ｐｈａｒｍ Ｂｉｏｔｅｃｈｎｏｌ． Ｖｏｌ．６, 199506, ｐｐ．２７７-２９６
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita
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