Title:
クロメン誘導体及びそのロイコトリエン生合成阻害のための使用
Document Type and Number:
Japanese Patent JP2010540518
Kind Code:
A
Abstract:
This invention provides novel salt and crystalline forms thereof of (−)4-(4-fluorophenyl)-7-[({5-[1-hydroxy-1-(trifluoromethyl)propyl]-1,3,4-oxadiazol-2-yl}amino)-methyl]-2H-chromen-2-one. The compounds are 5-LO inhibitors and are useful for treatment of conditions such as asthma, allergic rhinitis, COPD, and atherosclerosis.
Inventors:
Goslin, Francis
Vicky, Vicky
Vicky, Vicky
Application Number:
JP2010526918A
Publication Date:
December 24, 2010
Filing Date:
September 23, 2008
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C07D413/12; A61K31/4245; A61P1/04; A61P1/16; A61P1/18; A61P5/24; A61P7/02; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P11/02; A61P11/06; A61P13/12; A61P15/06; A61P15/10; A61P17/00; A61P17/10; A61P19/02; A61P19/08; A61P25/00; A61P25/06; A61P25/22; A61P25/24; A61P27/14; A61P35/02; A61P37/00; A61P37/06; A61P37/08; A61P43/00
Attorney, Agent or Firm:
Yokoyama Isao