Title:
肥満症治療における肥満細胞安定化薬
Document Type and Number:
Japanese Patent JP2010540519
Kind Code:
A
Abstract:
The present invention is directed to methods of treating or preventing the development of obesity by administering compounds that stabilize mast cells. In addition, it includes pharmaceutical compositions which have both a mast cell stabilizer and instructions regarding the use of the stabilizer in treating or preventing obesity.
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Inventors:
Sea, Guo-Pin
Application Number:
JP2010526924A
Publication Date:
December 24, 2010
Filing Date:
September 24, 2008
Export Citation:
Assignee:
The Briham and Women's Hospital, Incorporated
International Classes:
A61K31/275; A61K31/352; A61K31/436; A61K31/4535; A61P3/04; C07D311/24; C07D409/04; C07D491/052
Other References:
JPN6013030904; ＡＶＥＮＥＬＬ，Ａ． ｅｔ ａｌ: 'Ｗｈａｔ ｉｎｔｅｒｖｅｎｔｉｏｎｓ ｓｈｏｕｌｄ ｗｅ ａｄｄ ｔｏ ｗｅｉｇｈｔ ｒｅｄｕｃｉｎｇ ｄｉｅｔｓ ｉｎ ａｄｕｌｔｓ ｗｉｔｈ ｏｂｅｓｉｔｙ？ Ａ ｓｙｓｔｅｍａｔｉｃ ｒｅｖｉｅ' ＪＯＵＲＮＡＬ ＯＦ ＨＵＭＡＮ ＮＵＴＲＩＴＩＯＮ ＡＮＤ ＤＩＥＴＥＴＩＣＳ Ｖｏｌ． １７， Ｎｏ．４, 2004, ｐ．２９３-３１６
JPN6013030906; ＬＩＵ，Ｊ． ｅｔ ａｌ: 'Ｇｅｎｅｔｉｃ ｄｅｆｉｃｉｅｎｃｙ ａｎｄ ｐｈａｒｍａｃｏｌｏｇｉｃａｌ ｓｔａｂｉｌｉｚａｔｉｏｎ ｏｆ ｍａｓｔ ｃｅｌｌｓ ｒｅｄｕｃｅ ｄｉｅｔ-ｉｎｄｕｃｅｄ ｏｂｅｓｉｔｙ ａｎｄ ｄ' ＮＡＴＵＲＥ ＭＥＤＩＣＩＮＥ Ｖｏｌ．１５， Ｎｏ．８, 2009, ｐ．９４０-９４５
JPN6013030902; ＳＣＨＷＡＲＺＥＲ，Ｇ． ｅｔ ａｌ: 'Ｋｅｔｏｔｉｆｅｎ ａｌｏｎｅ ｏｒ ａｓ ａｄｄｉｔｉｏｎａｌ ｍｅｄｉｃａｔｉｏｎ ｆｏｒ ｌｏｎｇ-ｔｅｒｍ ｃｏｎｔｒｏｌ ｏｆ ａｓｔｈｍａ ａｎｄ ｗｈｅｅｚｅ ｉｎ ｃｈｉｌｄｒｅｎ' Ｃｏｃｈｒａｎｅ Ｄａｔａｂａｓｅ Ｓｙｓｔ Ｒｅｖ． Ｖｏｌ．１, 2004, ＣＤ００１３８４
JPN6013030904; ＡＶＥＮＥＬＬ，Ａ． ｅｔ ａｌ: 'Ｗｈａｔ ｉｎｔｅｒｖｅｎｔｉｏｎｓ ｓｈｏｕｌｄ ｗｅ ａｄｄ ｔｏ ｗｅｉｇｈｔ ｒｅｄｕｃｉｎｇ ｄｉｅｔｓ ｉｎ ａｄｕｌｔｓ ｗｉｔｈ ｏｂｅｓｉｔｙ？ Ａ ｓｙｓｔｅｍａｔｉｃ ｒｅｖｉｅ' ＪＯＵＲＮＡＬ ＯＦ ＨＵＭＡＮ ＮＵＴＲＩＴＩＯＮ ＡＮＤ ＤＩＥＴＥＴＩＣＳ Ｖｏｌ． １７， Ｎｏ．４, 2004, ｐ．２９３-３１６
JPN6013030906; ＬＩＵ，Ｊ． ｅｔ ａｌ: 'Ｇｅｎｅｔｉｃ ｄｅｆｉｃｉｅｎｃｙ ａｎｄ ｐｈａｒｍａｃｏｌｏｇｉｃａｌ ｓｔａｂｉｌｉｚａｔｉｏｎ ｏｆ ｍａｓｔ ｃｅｌｌｓ ｒｅｄｕｃｅ ｄｉｅｔ-ｉｎｄｕｃｅｄ ｏｂｅｓｉｔｙ ａｎｄ ｄ' ＮＡＴＵＲＥ ＭＥＤＩＣＩＮＥ Ｖｏｌ．１５， Ｎｏ．８, 2009, ｐ．９４０-９４５
JPN6013030906; ＬＩＵ，Ｊ． ｅｔ ａｌ: 'Ｇｅｎｅｔｉｃ ｄｅｆｉｃｉｅｎｃｙ ａｎｄ ｐｈａｒｍａｃｏｌｏｇｉｃａｌ ｓｔａｂｉｌｉｚａｔｉｏｎ ｏｆ ｍａｓｔ ｃｅｌｌｓ ｒｅｄｕｃｅ ｄｉｅｔ-ｉｎｄｕｃｅｄ ｏｂｅｓｉｔｙ ａｎｄ ｄ' ＮＡＴＵＲＥ ＭＥＤＩＣＩＮＥ Ｖｏｌ．１５， Ｎｏ．８, 2009, ｐ．９４０-９４５
JPN6013030902; ＳＣＨＷＡＲＺＥＲ，Ｇ． ｅｔ ａｌ: 'Ｋｅｔｏｔｉｆｅｎ ａｌｏｎｅ ｏｒ ａｓ ａｄｄｉｔｉｏｎａｌ ｍｅｄｉｃａｔｉｏｎ ｆｏｒ ｌｏｎｇ-ｔｅｒｍ ｃｏｎｔｒｏｌ ｏｆ ａｓｔｈｍａ ａｎｄ ｗｈｅｅｚｅ ｉｎ ｃｈｉｌｄｒｅｎ' Ｃｏｃｈｒａｎｅ Ｄａｔａｂａｓｅ Ｓｙｓｔ Ｒｅｖ． Ｖｏｌ．１, 2004, ＣＤ００１３８４
JPN6013030904; ＡＶＥＮＥＬＬ，Ａ． ｅｔ ａｌ: 'Ｗｈａｔ ｉｎｔｅｒｖｅｎｔｉｏｎｓ ｓｈｏｕｌｄ ｗｅ ａｄｄ ｔｏ ｗｅｉｇｈｔ ｒｅｄｕｃｉｎｇ ｄｉｅｔｓ ｉｎ ａｄｕｌｔｓ ｗｉｔｈ ｏｂｅｓｉｔｙ？ Ａ ｓｙｓｔｅｍａｔｉｃ ｒｅｖｉｅ' ＪＯＵＲＮＡＬ ＯＦ ＨＵＭＡＮ ＮＵＴＲＩＴＩＯＮ ＡＮＤ ＤＩＥＴＥＴＩＣＳ Ｖｏｌ． １７， Ｎｏ．４, 2004, ｐ．２９３-３１６
JPN6013030906; ＬＩＵ，Ｊ． ｅｔ ａｌ: 'Ｇｅｎｅｔｉｃ ｄｅｆｉｃｉｅｎｃｙ ａｎｄ ｐｈａｒｍａｃｏｌｏｇｉｃａｌ ｓｔａｂｉｌｉｚａｔｉｏｎ ｏｆ ｍａｓｔ ｃｅｌｌｓ ｒｅｄｕｃｅ ｄｉｅｔ-ｉｎｄｕｃｅｄ ｏｂｅｓｉｔｙ ａｎｄ ｄ' ＮＡＴＵＲＥ ＭＥＤＩＣＩＮＥ Ｖｏｌ．１５， Ｎｏ．８, 2009, ｐ．９４０-９４５
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita