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Title:
トリ置換された1,2,4-トリアゾール
Document Type and Number:
Japanese Patent JP2011500625
Kind Code:
A
Abstract:
The present invention relates to substituted 1-(alkyl)-3-aniline-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I). The invention particularly relates to potent positive allosteric modulators of nicotinic acetylcholine receptors which have the capability of increasing the efficacy of nicotinic receptor agonists.

Inventors:
Touring, Johannes Wilhelms Jiyon Ef
Deincro, Theodorus
Roussajyu, Anne Simone Giosephine
De Bruin, Marcel Franc Leopold
Tuan, Way
Application Number:
JP2010529361A
Publication Date:
January 06, 2011
Filing Date:
October 15, 2008
Export Citation:
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Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D401/04; A61K31/4439; A61P25/04; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P43/00
Domestic Patent References:
JP2006515313A2006-05-25
JP2009534357A2009-09-24
Foreign References:
WO2007031440A22007-03-22
WO2003094831A22003-11-20
WO2006078621A22006-07-27
Attorney, Agent or Firm:
Patent business corporation Odashima patent office