Title:
1種または複数の物質を段階的に放出させるためのマルチパートカプセル
Document Type and Number:
Japanese Patent JP2011500626
Kind Code:
A
Abstract:
A multipart capsule, e.g., a dosage form, is provided which includes a plurality of capsule portions, at least one of which contains a substance to be released into a gastro-intestinal environment and at least one link component interconnecting two adjacent capsule portions. At least one capsule portion is formed from a polymer that is a transitional polymer, for example, a polymer that changes shape, form, or structure within a gastro-intestinal environment, e.g., dispersible, dissolvable, disintegrable, fracturable, breachable, swellable, partially or completely soluble, or otherwise changeable when exposed to stomach pH and/or in intestine pH to thereby release the substance. The capsule portions are connected together in an assembled dosage form. The link component includes at least one aperture in flow communication with interiors of two adjacent capsule portions to control the release of the substance.
Inventors:
Steven Mark McAlister
Wayne M Matthews
Wayne M Matthews
Application Number:
JP2010529362A
Publication Date:
January 06, 2011
Filing Date:
October 15, 2008
Export Citation:
Assignee:
GLAXO GROUP LIMITED
International Classes:
A61K9/52; A61K47/34; A61K47/38
Domestic Patent References:
| JP2003505498A | 2003-02-12 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Mitsutaka Iwasaki
Michiko Matsutani
Nishino Mitsuru
Sakurai Yoko
Satoshi Hashimoto
Yasushi Ochiai
Mizuhara Masahiro
Hiroshi Yamazaki
Mitsutaka Iwasaki
Michiko Matsutani
Nishino Mitsuru
Sakurai Yoko
Satoshi Hashimoto
Yasushi Ochiai
Mizuhara Masahiro