Title:
プロゲステロン受容体アンタゴニスト
Document Type and Number:
Japanese Patent JP2013519640
Kind Code:
A
Abstract:
The invention relates to 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives of formula I with progesterone-antagonizing action and methods of production thereof, use thereof for the treatment and/or prevention of diseases and use thereof for producing medicinal products for the treatment and/or prevention of diseases, in particular uterine fibroids (myomata, uterine leiomyomata), endometriosis, heavy menstrual bleeding, meningiomata, hormone-dependent breast cancers and menopause-associated complaints or for fertility control and emergency contraception.
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Inventors:
Wolfgang Schwede
Ulrich Klar
Karsten Mellar
Andrea Rothgeri
Wilhelm Bourne
Christoph Houve
Ulrich Klar
Karsten Mellar
Andrea Rothgeri
Wilhelm Bourne
Christoph Houve
Application Number:
JP2012552361A
Publication Date:
May 30, 2013
Filing Date:
February 08, 2011
Export Citation:
Assignee:
Bayer Intellectual Property GmbH
International Classes:
C07J1/00; A61K31/569; A61P5/36; A61P15/00; A61P15/08; A61P15/12; A61P15/18; A61P35/00
Domestic Patent References:
| JPH06157587A | 1994-06-03 |
Other References:
FUHRMANN U, JOURNAL OF MEDICINAL CHEMISTRY, vol. V43N26, JPN6014046266, 2000, US, pages 5010 - 5016, ISSN: 0002931987
野崎正勝ら, 創薬化学, JPN6012059719, 1995, pages 98 - 99, ISSN: 0002931988
野崎正勝ら, 創薬化学, JPN6012059719, 1995, pages 98 - 99, ISSN: 0002931988
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Satoshi Hashimoto
Nishino Mitsuru
Takuji Yamada
Michiko Matsutani
Satoshi Hashimoto
Nishino Mitsuru