Title:
プロゲステロン受容体アンタゴニスト
Document Type and Number:
Japanese Patent JP2013519641
Kind Code:
A
Abstract:
The invention relates to 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives of the formula I with a progesterone antagonizing effect and processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and also their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular of uterus fibroids (myomas, uterine leiomyomas), endometriosis, heavy menstrual bleeding, meningiomas, hormone-dependent breast cancers and troubles associated with the menopause or for monitoring fertility and emergency contraception.
Inventors:
Wolfgang Schwede
Ulrich Klar
Karsten Mellar
Andrea Rothgeri
Wilhelm Bourne
Christoph Houve
Ulrich Klar
Karsten Mellar
Andrea Rothgeri
Wilhelm Bourne
Christoph Houve
Application Number:
JP2012552362A
Publication Date:
May 30, 2013
Filing Date:
February 08, 2011
Export Citation:
Assignee:
Bayer Intellectual Property GmbH
International Classes:
C07J41/00; A61K31/573; A61K31/58; A61K45/00; A61P15/00; A61P15/18; A61P35/00; C07J43/00
Domestic Patent References:
| JP2012533578A | 2012-12-27 | |||
| JP2012533578A | 2012-12-27 |
Foreign References:
| WO2008058767A1 | 2008-05-22 | |||
| WO2008058767A1 | 2008-05-22 |
Other References:
JPN6014046270; Ｓｔｅｒｏｉｄｓ Ｖ５９, 1994, Ｐ２２-２６
JPN6014046270; Ｓｔｅｒｏｉｄｓ Ｖ５９, 1994, Ｐ２２-２６
JPN6014046270; Ｓｔｅｒｏｉｄｓ Ｖ５９, 1994, Ｐ２２-２６
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Satoshi Hashimoto
Nishino Mitsuru
Takuji Yamada
Michiko Matsutani
Satoshi Hashimoto
Nishino Mitsuru