Title:
ジアリールアセチレンヒドラジドを含有するチロシンキナーゼ阻害剤
Document Type and Number:
Japanese Patent JP2014510037
Kind Code:
A
Abstract:
The present invention relates to novel diarylacetylene hydrazide compounds of formula (I) or pharmaceutically acceptable salt thereof, as tyrosine kinase inhibitors, the process for their preparation, and to the use of the compounds of formula (I) in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders related to tyrosine kinases, in warm-blooded animals.
Inventors:
Praval Sengupta
Hemant Asfubinbuhai Chokushi
Chetan Suljito Thing Fupuri
Subvil Hussen Yousuf Buhai Cimanwara
Balun Anil Kumar Mefta
Doi Paris Manubuhai Desai
Trinado Harao Chitotouri
Rajamannal Tohenna Toy
Jonathan David Marc Atkinson
Hemant Asfubinbuhai Chokushi
Chetan Suljito Thing Fupuri
Subvil Hussen Yousuf Buhai Cimanwara
Balun Anil Kumar Mefta
Doi Paris Manubuhai Desai
Trinado Harao Chitotouri
Rajamannal Tohenna Toy
Jonathan David Marc Atkinson
Application Number:
JP2013549896A
Publication Date:
April 24, 2014
Filing Date:
January 23, 2012
Export Citation:
Assignee:
Sumpu Haruma Advanced Research Company Limited
International Classes:
C07D213/56; C07D215/14; C07D239/26; C07D239/74; C07D241/12; C07D277/64; C07D401/12; C07D409/12; C07D417/12; C07D471/04; C07D487/04; A61K31/428; A61K31/437; A61K31/4406; A61K31/47; A61K31/4709; A61K31/496; A61K31/4965; A61K31/4985; A61K31/5025; A61K31/505; A61K31/517; A61P43/00
Domestic Patent References:
| JP2009521462A | 2009-06-04 | |||
| JP2003206273A | 2003-07-22 | |||
| JP2009521462A | 2009-06-04 | |||
| JP2003206273A | 2003-07-22 |
Foreign References:
| WO2009100536A1 | 2009-08-20 | |||
| WO2005094822A1 | 2005-10-13 | |||
| WO2009100536A1 | 2009-08-20 | |||
| WO2005094822A1 | 2005-10-13 |
Attorney, Agent or Firm:
Toru Ishikawa