Title:
HUMANIZED MONOCLONAL ANTIBODIES AND METHODS OF USE FOR THE DIAGNOSIS AND TREATMENT OF COLON AND PANCREAS CANCER
Document Type and Number:
Japanese Patent JP2019080572
Kind Code:
A
Abstract:
To provide diagnostic methods and therapeutic methods against cancer including lung cancer, ovarian cancer, pancreatic cancer, breast cancer, and colon cancer.SOLUTION: Provided is a humanized 31.1 monoclonal antibody (NEO-300 antibody) that selectively binds to the 31.1 epitope on the A33 protein differentially expressed in cancers.SELECTED DRAWING: Figure 3
Inventors:
WANG XUE-PING
PHILIP M ARLEN
PHILIP M ARLEN
Application Number:
JP2019007924A
Publication Date:
May 30, 2019
Filing Date:
January 21, 2019
Export Citation:
Assignee:
PREC BIOLOG INC
International Classes:
C12N15/13; A61K38/18; A61K38/19; A61K39/395; A61K45/00; A61K47/68; A61K49/06; A61K49/16; A61K51/10; A61P35/00; A61P35/04; A61P43/00; C07K16/30; C07K16/46; C12P21/08; G01N33/574
Foreign References:
| WO2006028197A1 | 2006-03-16 | |||
| WO2006004950A2 | 2006-01-12 | |||
| WO2011163401A2 | 2011-12-29 | |||
| US20080227965A1 | 2008-09-18 | |||
| US20080200654A1 | 2008-08-21 |
Attorney, Agent or Firm:
Osamu Yamamoto
Shinjiro Ono
Toru Miyamae
Motoharu Nakanishi
Takumi Terachi
Shinjiro Ono
Toru Miyamae
Motoharu Nakanishi
Takumi Terachi