Title:
【発明の名称】4‐ハロ‐3‐ヒドロキシブチロニトリルの製造法
Document Type and Number:
Japanese Patent JP2840722
Kind Code:
B2
Abstract:
A process for the production of a 4-halo-3-hydroxybutyronitrile which comprises reacting a 1,3-dihalo-2-propanol with a dehalogenating enzyme originating from a Corynebacterium or a Microbacterium in the presence of an alkali cyanide to thereby convert the 1,3-dihalo-2-propanol into the 4-halo-3-hydroyxbutyronitrile and collecting the product thus formed is disclosed. According to this process, a 4-halo-3-hydroxybutyronitrile which is highly useful in the syntheses of various medicines and physiologically active substances can be easily and efficiently produced from an inexpensive starting material.
Inventors:
NAKAMURA TETSUJI
TO FUJIO
WATANABE ICHIRO
TO FUJIO
WATANABE ICHIRO
Application Number:
JP18599189A
Publication Date:
December 24, 1998
Filing Date:
July 20, 1989
Export Citation:
Assignee:
NITSUTO KAGAKU KOGYO KK
International Classes:
C12N1/20; C12P13/00; C12R1/15; C12R1/32; (IPC1-7): C12P13/00
Domestic Patent References:
| JP5219965A | ||||
| JP4278089A |