Title:
ヘルパーウイルスを含まないAAV産生
Document Type and Number:
Japanese Patent JP4108746
Kind Code:
B2
Abstract:
A method for the production of adeno-associated virus stocks and recombinant adeno-associated virus stocks that are substantially free of contaminating helper virus is described. The method utilizes transfection with helper virus vectors to replace the infection with helper virus used in the conventional method.
Inventors:
Ferrari, Forest Kay.
Guiao, Guiao
Samulsky, Richard Jay.
Guiao, Guiao
Samulsky, Richard Jay.
Application Number:
JP50173097A
Publication Date:
June 25, 2008
Filing Date:
June 06, 1996
Export Citation:
Assignee:
University of North Carolina at Chapel Hill
International Classes:
C12N15/09; A61K35/76; A61K48/00; C12N5/10; C12N7/00; C12N15/864; C12P21/02; C12R1/91
Other References:
J. Virol., 米国, 1989年, Vol.63, No.9, 3822-3828
Proc. Natl. Acad. Sci., 米国, 1994年, Vol.91, 8802-8806
J. Virol., 米国, 1998年 3月, Vol.72, No.3, 2224-2232
Proc. Natl. Acad. Sci., 米国, 1994年, Vol.91, 8802-8806
J. Virol., 米国, 1998年 3月, Vol.72, No.3, 2224-2232
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Mitsutaka Iwasaki
Shoji Nakajima