Title:
分解再構築ウイルス様粒子を含むヒトパピローマウイルスワクチン
Document Type and Number:
Japanese Patent JP4594534
Kind Code:
B2
Abstract:
Human Papillomavirus vaccine formulations which contain virus-like particles (VLPs) can be made more stable and have an enhanced shelf-life, by treating the VLPs to a disassembly and reassembly process. Also provided are formulation buffers to long term stable storage of VLPs.
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Inventors:
Bolkin, David Bee
Matsuha, Henryk
Lee
Matsuha, Henryk
Lee
Application Number:
JP2000607656A
Publication Date:
December 08, 2010
Filing Date:
March 22, 2000
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
A61K9/08; A61K39/12; A61K47/02; A61K47/14; A61K47/16; A61K47/34; A61P31/12
Foreign References:
| WO1998044944A1 |
Other References:
Virology,1998年,Vol.243,p.423-431
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Mitsuru Inoue
Akio Ichiiri
Katsuma Osaki
Takamasa Soma
Makoto Ono
Mitsuru Inoue
Akio Ichiiri
Katsuma Osaki
Takamasa Soma