Title:
医薬化合物をスクリーニングするためのシステムと方法
Document Type and Number:
Japanese Patent JP4638146
Kind Code:
B2
Abstract:
A method for obtaining a response of a tissue model system to an activator includes contacting a bio-artificial tissue model system with an activator and measuring cellular mechanical response thereto of at least one of contractile force and tissue stiffness. A method for obtaining a response of a tissue model system to an activator includes contacting a bio-artificial tissue model system with an activator and measuring cellular mechanical response thereto of at least one of contractile force and hysteresis.
Inventors:
Elson, Elson
MacConogee, William Bee.
Tetsuro Wakatsuki
MacConogee, William Bee.
Tetsuro Wakatsuki
Application Number:
JP2003521318A
Publication Date:
February 23, 2011
Filing Date:
August 14, 2002
Export Citation:
Assignee:
WASHINGTON UNIVERSITY IN ST.LOUIS
International Classes:
G01N33/50; C12N5/02; C12N5/06; C12N5/08; C12Q1/00; C12Q1/02; G01N3/38; G01N33/15; G01N3/00; G01N3/02
Other References:
J.Cell Biol.,1992年 4月 1日,Vol.117,p.73-82
JSME Int.J.SerA.Solid Mech.Mater.Eng.Soc.Mech.Engineers,1998年,Vol.41,No.4,p.576-583
FASEB J.,1997年,Vol.11,p.683-694
BED(AMERICAN SOCIETY OF MECHANICAL ENGINEERS), PROCEEDING OF THE 2001 BIOENGINEERING CONFERENCE,2001年 6月27日,VOL.50,P.353-354
BIOPHYSICAL JOURNAL,2000年,VOL.79,P.2353-2368
JSME Int.J.SerA.Solid Mech.Mater.Eng.Soc.Mech.Engineers,1998年,Vol.41,No.4,p.576-583
FASEB J.,1997年,Vol.11,p.683-694
BED(AMERICAN SOCIETY OF MECHANICAL ENGINEERS), PROCEEDING OF THE 2001 BIOENGINEERING CONFERENCE,2001年 6月27日,VOL.50,P.353-354
BIOPHYSICAL JOURNAL,2000年,VOL.79,P.2353-2368
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama