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Title:
2-ヒドロキシ酸モノマーを含む生体吸収性ポリマー
Document Type and Number:
Japanese Patent JP4780961
Kind Code:
B2
Abstract:
The present invention relates to a method of producing 2-hydroxyacid-containing polymer comprising expressing in an organism genes encoding a polyhydroxyalkanoate (PHA) synthase and at least one enzyme for the production of 2-hydroxyacyl Co-A. Preferably the method is a method of producing glycolic acid-containing polyhydroxyalkanoate polymer comprising feeding glycolic acid or a substrate converted to 2-hydroxyacid units to bacteria or plants expressing a polyhydroxyalkanoate (PHA) synthase and at least one enzyme for the production of 2-hydroxyacyl Co-A to produce the glycolic acid-containing polymer. The present invention also relates to the use of a laser to prepare a porous PHA polymer, by melt or solvent processing the PHA into a mold and perforating the material with the laser to achieve the desired porosity.

Inventors:
Martin, David P.
Scully, Frank A.
Application Number:
JP2004546663A
Publication Date:
September 28, 2011
Filing Date:
May 07, 2003
Export Citation:
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Assignee:
Metabolics, Incorporated
Tefa, Inc.
International Classes:
C12P7/62; C12N15/09; C12R1/19
Foreign References:
WO2000056376A12000-09-28
WO1999032536A11999-07-01
WO2002008428A22002-01-31
Attorney, Agent or Firm:
Yoshio Kawaguchi
Atsushi Okamoto
Kayo Shiina
Chihiro Watanabe
Katsuma Osaki
Mitsuaki Tsubokura
Chihiro Watanabe
Katsuma Osaki
Mitsuaki Tsubokura