Title:
疎水性薬物検体代謝産物との交差反応性が低下している免疫アッセイ
Document Type and Number:
Japanese Patent JP5174898
Kind Code:
B2
Abstract:
The present disclosure provides among other things immunoassays exhibiting reduced cross-reactivity with analyte metabolites. Additionally, the present disclosure provides diagnostic immunoassays to determine the concentration or level in a test sample of a hydrophobic drug that metabolizes in vivo or in vitro to form cross-reacting metabolites wherein cross-reactivity with such metabolites of the drug analyte is reduced. In particular, the disclosure provides such immunoassays where the hydrophobic drug is an immunosuppressant drug such as cyclosporine A.
Inventors:
Blait, Elaine M
Finley, David M
Hollets-McMauchs, Serie A
Pacientei, David P.
Ryan Yee, Pictel
Shields, Michael
Spring, Thomas G
One, Philip P
Finley, David M
Hollets-McMauchs, Serie A
Pacientei, David P.
Ryan Yee, Pictel
Shields, Michael
Spring, Thomas G
One, Philip P
Application Number:
JP2010509567A
Publication Date:
April 03, 2013
Filing Date:
May 23, 2008
Export Citation:
Assignee:
ABBOTT LABORATORIES
International Classes:
G01N33/543; G01N33/53; G01N33/531
Domestic Patent References:
JP4316599A | ||||
JP2003201298A |
Foreign References:
WO2007044978A1 |
Attorney, Agent or Firm:
Kawaguchi International Patent Office
Chihiro Watanabe
Katsuma Osaki
Mitsuaki Tsubokura
Chihiro Watanabe
Katsuma Osaki
Mitsuaki Tsubokura
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