Title:
高浸透性テルビナフィン製剤
Document Type and Number:
Japanese Patent JP5829217
Kind Code:
B2
Abstract:
The present invention provides topical compositions, methods of preparation, and methods of treatment for onychomychosis. In certain specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a zwitterionic surfactant or charged derivative thereof; a carboxylic acid, a lower alcohol, and water. The acid is selected from a short-chain hydroxy acid, a short-chain fatty acid, and a mixture thereof. In certain other specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a quarternary amino acid, a keratolytic agent; a lower alcohol; and water. In certain embodiments, the keratolytic agent is urea, ammonium thioglycolate, or a mixture thereof.
Inventors:
Buyuktimkin Serveto
Buyuk Timkin Nadia
Shin Jagato
Newsome John M.
King-Smith Dominique
Kisaku Edward
Buyuk Timkin Nadia
Shin Jagato
Newsome John M.
King-Smith Dominique
Kisaku Edward
Application Number:
JP2012546222A
Publication Date:
December 09, 2015
Filing Date:
December 22, 2010
Export Citation:
Assignee:
Nuvo Research Inc.
International Classes:
A61K31/137; A61K9/06; A61K9/08; A61K47/10; A61K47/12; A61K47/14; A61K47/18; A61K47/20; A61K47/36; A61K47/38; A61P31/10; A61P33/14
Domestic Patent References:
| JP2005501885A | ||||
| JP2006520800A | ||||
| JP2009540019A | ||||
| JP2011529038A |
Attorney, Agent or Firm:
Kenichi Morita
Kenjiro Yamaguchi
Kenjiro Yamaguchi