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Title:
生体組織用細胞接着性材料
Document Type and Number:
Japanese Patent JP5881611
Kind Code:
B2
Abstract:
An object of the present invention is to provide a cell-adhesive material for biological tissues, in which the surface of a material for biological tissues (particularly metallic material) is modified strongly with a large amount of a cell-adhesive artificial peptide (P) that retains a biological activity. The present invention provides a cell-adhesive material for biological tissues including a cell-adhesive artificial peptide (P) and a material for biological tissues, wherein the cell-adhesive artificial peptide (P) is immobilized on the surface of the material for biological tissues through an electrochemical reaction. The cell-adhesive artificial peptide (P) is preferably a peptide (P1) that is synthesized by a genetic recombinant microorganism and has at least one cell-adhesive minimal amino acid sequence (X) in one molecule. The number of the cell-adhesive minimal amino acid sequences (X) in one molecule of the polypeptide (P1) is preferably 3 to 50.

Inventors:
Yasuhiko Tabata
Shingo Kawabata
Application Number:
JP2012541864A
Publication Date:
March 09, 2016
Filing Date:
November 01, 2011
Export Citation:
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Assignee:
SANYO CHEMICAL INDUSTRIES,LTD.
Yasuhiko Tabata
International Classes:
A61L27/00; A61L29/00; A61L31/00
Domestic Patent References:
JP2005058772A2005-03-10
JP2005170810A2005-06-30
Foreign References:
WO2009154961A22009-12-23
WO2006004778A22006-01-12
Other References:
JPN6015027531; 'Placement of biomaterials and cells on University of Michigan neuroprobes.' Society for Neuroscience Abstracts Vol. 26, No. 1-2, 2000, pp. Abstract
Attorney, Agent or Firm:
Kenichi Sakurai