Title:
フィブロネクチン−ＥＤＡに対する免疫グロブリン様分子
Document Type and Number:
Japanese Patent JP6698529
Kind Code:
B2
Abstract:
The present invention is concerned with immunoglobulin (Ig)-like molecules or fragments thereof for use in treatment, prevention, or prevention of progression of adverse cardiac remodelling and conditions resulting from or relating to myocardial infarction and pressure-overload, such as heart failure, aneurysm formation and remote myocardial fibrosis and for use in improving angiogenesis, preferably after ischemic injury. The invention also provides nucleic acid molecules encoding said Ig-like molecules, vectors comprising same, and host cells comprising same.
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Inventors:
Arslan, Fatih
Application Number:
JP2016539063A
Publication Date:
May 27, 2020
Filing Date:
December 12, 2014
Export Citation:
Assignee:
UMSE Utrecht Holding Bf
International Classes:
C07K16/18; A61K35/12; A61K35/76; A61K39/395; A61K48/00; A61P9/00; A61P9/10; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N5/12; C12N15/13
Domestic Patent References:
| JP2010534237A |
Foreign References:
| WO2012057613A1 | ||||
| US5108898 | ||||
| US20090170751 |
Other References:
Circulation Research,2011年,Vol.108,p.582-592
Angiogenesis,2009年,Vol.12, No.2,p.165-175
JBC,1999年,Vol.274,p.17876-17884
Angiogenesis,2009年,Vol.12, No.2,p.165-175
JBC,1999年,Vol.274,p.17876-17884
Attorney, Agent or Firm:
Patent Business Corporation Takewa International Patent Office