Title:
【発明の名称】遺伝子転写産物の比較解析
Document Type and Number:
Japanese Patent JPH09503921
Kind Code:
A
Abstract:
A method and system for quantifying the relative abundance of gene transcripts in a biological sample. One embodiment of the method generates high-throughput sequence-specific analysis of multiple RNAs or their corresponding cDNAs (gene transcript imaging analysis). Another embodiment of the method produces a gene transcript imaging analysis by the use of high-throughput CDNA sequence analysis. In addition, the gene transcript imaging can be used to detect or diagnose a particular biological state, disease, or condition which is correlated to the relative abundance of gene transcripts in a given cell or population of cells. The invention provides a method for comparing the gene transcript image analysis from two or more different biological samples in order to distinguish between the two samples and identify one or more genes which are differentially expressed between the two samples.
Inventors:
Sailhammer Jeffrey Jay.
Scott Randall W.
Scott Randall W.
Application Number:
JP52021895A
Publication Date:
April 22, 1997
Filing Date:
January 27, 1995
Export Citation:
Assignee:
Insight Pharmaceuticals, Inc.
International Classes:
G01N33/48; C07H21/02; C07H21/04; C12N15/09; C12Q1/68; G06F17/30; G16B20/00; G16B30/10; G16B30/20; G16B35/10; G16B35/20; C40B30/02; C12Q; (IPC1-7): C12N15/09; C12Q1/68; G01N33/48
Attorney, Agent or Firm:
Shimizu Hatsushi