Title:
【発明の名称】条件致死遺伝子を利用する組成物及び方法
Document Type and Number:
Japanese Patent JPH09503920
Kind Code:
A
Abstract:
The present invention provides recombinant viral vectors carrying a vector construct which directs the expression of a gene product (eg. HSVTK) that activates a compound with little or no cytotoxicity into a toxic product. Also provided are methods of destroying or inhibiting pathogenic agents in a warm blooded animal, comprising the step of administering to the animal a viral vector such as that described above, in order to inhibit or destroy the pathogenic agent.
More Like This:
Inventors:
Barber, Jack Earl.
Glover, Harry E.
Jolly, Douglas Jay.
Glover, Harry E.
Jolly, Douglas Jay.
Application Number:
JP51460795A
Publication Date:
April 22, 1997
Filing Date:
November 18, 1994
Export Citation:
Assignee:
Chiron Beer Jean, Incorporated
International Classes:
C12N15/09; A61K35/76; A61K38/20; A61K38/21; A61K48/00; C07H21/04; C07K14/035; C12N5/10; C12N15/16; C12N15/85; C12N15/867; A61K38/00; A61K39/00; (IPC1-7): C12N15/09; A61K35/76; A61K48/00; C07H21/04; C12N5/10
Attorney, Agent or Firm:
Shusaku Yamamoto