Title:
4-Al kill - 3-methylene butyl = a manufacturing method of carboxylate
Document Type and Number:
Japanese Patent JP6249938
Kind Code:
B2
Abstract:
Provided is a simple, selective and efficient method for producing 4-alkyl-3-methylenebutyl carboxylates such as 7-methyl-3-methylene-7-octenyl propionate. More specifically provided is a method for producing a 4-alkyl-3-methylenebutyl carboxylate compound, the method comprising a diacyloxylation step of subjecting a 4-halo-2-halomethyl-1-butene compound (6) to diacyloxylation to obtain a 3-acyloxymethyl-3-butenyl carboxylate compound (3), and a coupling step of subjecting the 3-acyloxymethyl-3-butenyl carboxylate compound (3) to a coupling reaction with an organometallic reagent (4) to obtain the 4-alkyl-3-methylenebutyl carboxylate compound (5).
Inventors:
Tsuyoshi Kanao
Naoki Ishibashi
Yusuke Nagae
Naoki Ishibashi
Yusuke Nagae
Application Number:
JP2014262614A
Publication Date:
December 20, 2017
Filing Date:
December 25, 2014
Export Citation:
Assignee:
Shin-Etsu Chemical Co., Ltd.
International Classes:
C07C67/293; C07C67/10; C07C69/24; C07C69/28
Other References:
Tetrahedron Letters,1993年,34(14),2327-2330
Pyrolysis of Esters. XXI,1962年,1975-1978
Chem. Pharm. Bull.,1985年,33(1),41-47
Tetrahedron Asymmetry,1994年,5(4),691-698
J. Org. Chem.,1993年,58,3140-3147
Pyrolysis of Esters. XXI,1962年,1975-1978
Chem. Pharm. Bull.,1985年,33(1),41-47
Tetrahedron Asymmetry,1994年,5(4),691-698
J. Org. Chem.,1993年,58,3140-3147
Attorney, Agent or Firm:
Mitsuo Matsui
Hidefumi Kawamura
Hidefumi Kawamura