Title:
５−ヒドロキシピリミジン−４−カルボキサミド誘導体
Document Type and Number:
Japanese Patent JP5718236
Kind Code:
B2
Abstract:
The present invention provides a compound which enhances the production of erythropoietin. The present invention provides a compound represented by formula (1):
[wherein, R 1 : formula (1A) :
[wherein, R 4 and R 5 : H, halogen, or alkyl; R 6 : H, halogen, alkyl, or the like; R 7 : substitutable hydroxyalkyl, substitutable hydroxyhalo alkyl, substitutable alkoxyalkyl, or the like; substituent group ±: oxo, hydroxy, amino, or the like; ring Q 1 : a monocyclic heterocyclic group; ring Q 2 : a monocyclic hydrocarbon ring group, or a monocyclic heterocyclic group; ring Q 3 : a monocyclic hydrocarbon ring group, or a monocyclic heterocyclic group; X: a single bond, methylene, ethylene, or the like]; R 2 : alkyl, or methylsulfanyl; and R 3 : H, or methyl], or the like.
Inventors:
Ken Kuribayashi
Hideki Kubota
Naoki Tanaka
Go Fukuda
Takashi Tsuji
Goto Riki
Hideki Kubota
Naoki Tanaka
Go Fukuda
Takashi Tsuji
Goto Riki
Application Number:
JP2011537279A
Publication Date:
May 13, 2015
Filing Date:
October 20, 2010
Export Citation:
Assignee:
Daiichi Sankyo Co., Ltd.
International Classes:
C07D401/06; A61K31/506; A61P7/06; C07D401/14
Domestic Patent References:
| JP5341069B2 | 2013-11-13 | |||
| JP2011105708A | 2011-06-02 |
Foreign References:
| WO2009117269A1 | 2009-09-24 | |||
| WO2004108681A1 | 2004-12-16 | |||
| WO2006133391A2 | 2006-12-14 | |||
| WO2009131127A1 | 2009-10-29 | |||
| WO2009131129A1 | 2009-10-29 | |||
| WO2009117269A1 | 2009-09-24 | |||
| WO2004108681A1 | 2004-12-16 | |||
| WO2006133391A2 | 2006-12-14 | |||
| WO2009131127A1 | 2009-10-29 | |||
| WO2009131129A1 | 2009-10-29 |
Attorney, Agent or Firm:
Kimiki Ishibashi
Noriko Kitano
Imamura Mayu
Yukiko Nakamura
Toshiyasu Takemoto
Hironobu Kodama
Reiko Kanehara
Noriko Kitano
Imamura Mayu
Yukiko Nakamura
Toshiyasu Takemoto
Hironobu Kodama
Reiko Kanehara