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Title:
ACTIVITY INHIBITOR AND ACTIVITY-INHIBITING METHOD FOR TRPA1, AND SKIN CARE PREPARATION FOR EXTERNAL USE
Document Type and Number:
Japanese Patent JP2011140471
Kind Code:
A
Abstract:

To provide a TRPA1 activity inhibitor effectively inhibiting activation of TRPA1, a TRPA1 activity-inhibiting method effectively inhibiting activation of TRPA1, and a skin care preparation for external use of low irritating nature to the skin.

The TRPA1 activity inhibitor for inhibiting TRPA1 activity comprises a carbonate ion and/or a bicarbonate ion. The TRPA1 activity inhibitor for inhibiting TRPA1 activity comprises a substance that dissociates into a carbonate ion and/or a bicarbonate ion. The TRPA1 activity-inhibiting method for inhibiting TRPA1 activity comprises bringing a carbonate ion and/or a bicarbonate ion into contact with TRPA1. The skin care preparation for external use contains ammonia and further comprises a substance that dissociates into a carbonate ion and/or a bicarbonate ion.


Inventors:
FUJITA IKUNAO
HARA SHINYA
KANNO MANABU
KURIYAMA KENICHI
TSUJINO YOSHIO
Application Number:
JP2010002980A
Publication Date:
July 21, 2011
Filing Date:
January 08, 2010
Export Citation:
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Assignee:
MANDOM CORP
International Classes:
A61K33/10; A61K8/19; A61K33/02; A61P17/00; A61P25/02; A61P29/02; A61P43/00; A61Q19/00
Domestic Patent References:
JP2009035500A2009-02-19
JP2006188672A2006-07-20
Attorney, Agent or Firm:
Patent Business Corporation Suncrest International Patent Office



 
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