Title:
ALKYLTHIOCHALCONE DERIVATIVE
Document Type and Number:
Japanese Patent JPH023670
Kind Code:
A
Abstract:
NEW MATERIAL:A chalcone derivative expressed by the formula (R1 and R2 are 1-22C alkyl; m and n are 1-5).
EXAMPLE: 4-Methyl-4'-methylthiochalcone.
USE: A medicine having excellent pharmacological action, such as antimcrobial action, and utilizable in a wide range of fields, such as medicine.
PREPARATION: Various alkylthiobenzaldehydes and various alkylthioacetophenones are subjected to condensation reaction in the presence of a basic catalyst, such as NaOH, or acidic catalyst, such as BF3, preferably at 0-50°C for 30min-25hr to afford the compound expressed by the formula.
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Inventors:
HAYASHI AKIO
GOTO YOSHITAKA
NAKAYAMA MASAHARU
GOTO YOSHITAKA
NAKAYAMA MASAHARU
Application Number:
JP15243488A
Publication Date:
January 09, 1990
Filing Date:
June 22, 1988
Export Citation:
Assignee:
NIPPON OILS & FATS CO LTD
International Classes:
A61K31/12; A61P31/04; C07C323/22; (IPC1-7): A61K31/12; C07C323/22
Attorney, Agent or Firm:
Hajime Sakai (2 outside)
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