Title:
ANTI-ROR ANTIBODY CONSTRUCTS
Document Type and Number:
Japanese Patent JP2023168551
Kind Code:
A
Abstract:
To provide anti-ROR antibody constructs, pharmaceutical compositions comprising the constructs, and methods of use thereof.SOLUTION: In a certain embodiment, the ROR antigen is ROR1. In a certain embodiment, the ROR antigen is ROR2. In a certain embodiment, the ROR antigen is ROR1 and ROR2. In a certain embodiment, the ROR antigen is a domain selected from the group consisting of ROR1 Frizzle domain, ROR2 Frizzle domain, ROR1 Ig-like domain, ROR2 Ig-like domain, ROR1 Kringle domain and ROR2 Kringle domain. In a certain embodiment, the ROR antigen includes a human ROR antigen.SELECTED DRAWING: None
Inventors:
LUCAS BAILEY
LI QUFEI
MALGORZATA AGNIESZKA NOCULA-LUGOWSKA
BRYAN GLASER
LI QUFEI
MALGORZATA AGNIESZKA NOCULA-LUGOWSKA
BRYAN GLASER
Application Number:
JP2023172867A
Publication Date:
November 24, 2023
Filing Date:
October 04, 2023
Export Citation:
Assignee:
EXELIXIS INC
International Classes:
C07K16/28; A61K39/00; A61K39/395; A61K45/00; A61P35/00; A61P35/02; A61P37/04; C07K16/46
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Natsuki Morishita
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