ANTIBACTERIAL AGENT AND COMPOSITION FOR ORAL CAVITY CONTAINING THE SAME

Title:

ANTIBACTERIAL AGENT AND COMPOSITION FOR ORAL CAVITY CONTAINING THE SAME

Document Type and Number:

Japanese Patent JP3522930

Kind Code:

B2

Abstract:

PROBLEM TO BE SOLVED: To obtain an antibacterial agent inhibiting growth of bacteria causing dental caries, periodontosis and halitosis, etc., containing a sesquiterpene compound.
SOLUTION: This antibacterial agent contains at least one kind of a sesquiterpene compound expressed by the formula (R1 and R2 are each H or hydroxyl; R3 and R4 are each H, hydroxyl or carbonyl together with C; a broken line may be a double bond) as an active component. A composition for oral cavity is obtained by including 0.0001-10wt.%, preferably 0.001-5wt.% of at least one kind of the compound of the formula as an active component. The compound of the formula is obtained by extracting Curcuma longa or a plant belonging to the genus Curcuma other than Curcuma longa, or by a chemical synthesis. This antibacterium agent suppresses growth of a Streptococcus mutans as a pathogenic fungus of dental caries, Porphyromonas gingivalis as a pathogenic fungus of periodontosis, Fusobacterium nucleatum as a causing bacterium of halitosis and Propionibacterium acnes as a causing bacterium of a pimple and almost does not exhibit an effect to Escherichia coil as an enteral bacterium.

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Inventors:

Hori, Takashi
Kanazawa, Satoshi
Nishizawa, Yoshinori
Oshino, Kazushi
Eguchi, Yasuteru

Application Number:

JP31790195A

Publication Date:

April 26, 2004

Filing Date:

December 06, 1995

Export Citation:

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Assignee:

KAO CORP

International Classes:

A61K8/00; A01N31/04; A01N35/02; A61K8/33; A61K31/05; A61K31/12; A61P1/02; A61P31/04; A61Q11/00; C07C33/30; C07C49/213; C07C49/245; (IPC1-7): A61K7/16; A61K31/05; A61K31/12; A61P1/02

Other References:

ＢＥＲＯＵＳＯＶＡ，Ｎ．ｅｔａｌ，ＥｓｓｅｎｔｉａｌｏｉｌｓｉｎＬｅｄｕｍＬ．ａｎｔｉｆｕｎｇａｌｐｒｏｐｅｒｔｉｅｓ，Ｋｈｉｍｉｋｏ−ＦａｒｍａｔｓｅｖｔｉｃｈｅｓｋｉｉＺｈｕｒｎａｌ，１９８９年，Ｖｏｌ．２３，Ｎｏ．３，ｐｐ３１７−３１９
ＭｃＥＮＲＯＥ，ＦｒａｎｋＪ．ｅｔａｌ，Ｔｅｔｒａｈｅｄｒｏｎ，１９７８年，Ｖｏｌ．３４，Ｎｏ．１１，ｐｐ１６６１−１６６４

Attorney, Agent or Firm:

特許業務法人アルガ特許事務所（外４名）

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