Title:
ASYMMETRIC EPOXIDIZING REACTION OF CYCLOALKADIENES
Document Type and Number:
Japanese Patent JP3921696
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To readily obtain the subject compound useful as a synthetic intermediate for a medicine and an agrochemical by subjecting a specific 1,3- cycloalkadiene compound to an asymmetric epoxidizing reaction using a specific optically active manganese complex catalyst.
SOLUTION: A 1,3-cycloalkadiene compound expressed by formula I[(n) is an integer of 1-8; Z1-Z6 are each H, a halogen, a 1-4C alkyl, a (substituted) phenyl, a 1-4C alkoxy, a 2-5C alkanoyl, a 2-5C alkoxycarbonyl, nitro, cyano, etc.] is subjected to an asymmetric epoxidizing reaction by using an optically active manganese complex expressed by formula II[R1-R4 are each H, a 1-4C alkyl, a (substituted) phenyl, etc.; R is H, a 1-4C alkyl, a (substituted) phenyl or a substituted silyl; X- is an anion capable of forming a salt; Y is H, a halogen, a 1-4C alkyl, a 1-4C alkoxy, nitro or cyano] as a catalyst to obtain the objective optically active cycloalkadiene monoepoxy compound expressed by formula III(the absolute configuration of carbon atom expressed by * denotes R or S).
Inventors:
Katsuki Tsutomu
Application Number:
JP20322095A
Publication Date:
May 30, 2007
Filing Date:
August 09, 1995
Export Citation:
Assignee:
Nissan Chemical Industry Co., Ltd.
International Classes:
C07D303/02; B01J31/22; C07B53/00; C07B61/00; (IPC1-7): C07D303/02; B01J31/22; //C07B53/00; C07B61/00; C07M7:00
Foreign References:
| US5420314 |
Other References:
Tetrahedron Letters,1994, Vol.35, No.5,pp.669-372
Previous Patent: TREATMENT METHOD FOR MANGANESE-CONTAINING WASTEWATER
Next Patent: LITHIUM MANGANESE SPINEL AND ITS PRODUCTION AND ITS USE
Next Patent: LITHIUM MANGANESE SPINEL AND ITS PRODUCTION AND ITS USE