Title:
ASYMMETRIC SYNTHESIS METHOD OF ORGANIC PHOSPHORUS COMPOUND
Document Type and Number:
Japanese Patent JP3865297
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide an asymmetric synthesis method to industrially, advantageously and efficiently obtain an optically active organic phosphorus compound.
SOLUTION: In the asymmetric synthesis method of the organic phosphorus compound represented by general formula (3) (wherein R1 and R2 are each a monovalent organic group, a hydrogen atom or a hydroxyl group. R1 and R2 are not the same groups. A is a sulfur atom or an oxygen atom. Q is an organic group formed by eliminating active hydrogen. * is asymmetric phosphorus atom), a racemate of a halogenated organic phosphorus compound represented by general formula (1) (wherein R1, R2 and A are equivalent to the above. X is a halogen atom) and an active hydrogen-containing compound represented by H-Q (wherein Q is equivalent to the above) are reacted in the presence of a base and a chiral phase-transfer catalyst.
Inventors:
Ken Tamura
Ryukoku Eiichi
Ryukoku Eiichi
Application Number:
JP2001326309A
Publication Date:
January 10, 2007
Filing Date:
October 24, 2001
Export Citation:
Assignee:
Nippon Chemical Industry Co., Ltd.
International Classes:
C07B53/00; C07F9/6539; A01N57/32; C07B61/00; A01P5/00; A01P7/02; A01P7/04; (IPC1-7): C07F9/6539; //A01N57/32; C07B53/00; C07B61/00; C07M7:00
Domestic Patent References:
| JP3261792A | ||||
| JP2088590A | ||||
| JP7070040A | ||||
| JP11080036A |
Attorney, Agent or Firm:
Tokuhiro Watanabe