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Patent Searching and Data


Title:
BACTERIAL ENDOTOXIN ADSORBENT AND METHOD FOR SCREENING THE SAME
Document Type and Number:
Japanese Patent JP2007031448
Kind Code:
A
Abstract:

To provide an easily synthesizable new lipopolysaccharide adsorbent (bacterial endotoxin adsorbent), enabling easy adjustment of various relating structures, and usable for the adsorption of various lipopolysaccharides and provide a screening method for the adsorbent.

The method for the screening of a bacterial endotoxin adsorbent comprises the binding assay (binding experiment) of a peptide library and a radioactive labeled lipid A produced by introducing a radioactive element to a phosphonoxyethyl derivative of a biosynthesis precursor-type lipid A or an E.coli-type lipid A. The invention further relates to a bacterial endotoxin adsorbent composed of a specific peptide library found by the screening method.


Inventors:
FUKASE KOICHI
HANS PETER NESSLER
Application Number:
JP2006281025A
Publication Date:
February 08, 2007
Filing Date:
October 16, 2006
Export Citation:
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Assignee:
JAPAN SCIENCE & TECH AGENCY
International Classes:
C07K7/06; B01J20/26
Attorney, Agent or Firm:
Norio Saeki